THYROID ACTIVITY IN RELATION TO PROGNOSIS IN MAMMARY CANCER
THYROID ACTIVITY IN RELATION TO PROGNOSIS IN MAMMARY CANCER
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DOI:
10.1038/bjc.1967.60
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发表时间:
1967-01-01
影响因子:
8.8
通讯作者:
WATERHOUSE, JA
中科院分区:
文献类型:
--
作者:
SICHER, K;WATERHOUSE, JA
The influence of thyroid activity on prognosis in breast cancer was reported. Two measures of thyroid activity were used, the uptake at the 24th hr. ("B") of tracer doses of 131I and the assay of protein-bound iodine (PBI), which are closely equivalent in practice. Patients who survived 5 years from an initial measurement of B were assessed in the same way again, and showed a slight reduction, not statistically significant, in thyroid activity. In relation to their initial measurements the actual fate of patients 5 years later appeared to show no evidence of the influence of thyroid activity. This apparently anomalous conclusion, conforming with others in the literature, is attributed to the possible use of an inappropriate measure of activity. A measurement of the gland''s potential activity by its response to exogenous stimulation should be attempted.