Diversification reactions of γ-silyl allenyl esters: selective conversion to all-carbon quaternary centers and γ-allene dicarbinols.
Diversification reactions of γ-silyl allenyl esters: selective conversion to all-carbon quaternary centers and γ-allene dicarbinols.
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γ-甲硅烷基联烯基酯的多样化反应：选择性转化为全碳季中心和γ-丙二烯二甲醇。
DOI：
10.1039/c7cc01708a
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Lepore,SalvatoreD
中科院分区：
文献类型：
--
作者：
Jana,Susovan;Roy,Animesh;Lepore,SalvatoreD
描述了γ-硅丙二烯酯独特的反应活性。利用甲硅烷基作为氟化物受体，这些联烯酸酯容易地经历了除了各种亲电选择性地产生产品与全碳季中心或联烯酸二甲醇。这些二甲醇随后被转化为新的高度取代的6-氢-2-吡喃酮。
The unique reactivity of γ-silyl allenyl esters is described. Taking advantage of the silyl group as a fluoride acceptor, these allenoates readily underwent addition to a variety of electrophiles to selectively yield products with all-carbon quaternary centers or allenoate dicarbinols. These dicarbinols were subsequently converted to novel highly substituted 6-hydro-2-pyrones.