Adalimumab-induced autoimmune hepatitis.
Adalimumab-induced autoimmune hepatitis.
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DOI：
10.1097/mcg.0b013e3181a745e7
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发表时间：
2010-01-01
影响因子：
2.9
通讯作者：
Shibolet, Oren
中科院分区：
文献类型：
--
作者：
Adar, Tomer;Mizrahi, Meir;Shibolet, Oren
抗肿瘤坏死因子抗体广泛用于治疗自身免疫性疾病。我们描述了发生自身免疫性肝炎的患者治疗阿达木单抗，一个完全人IgG抗体抗肿瘤坏死因子，银屑病关节炎。停用阿达木单抗和类固醇治疗后，患者完全恢复。这是阿达木单抗诱导的自身免疫性肝炎的首例报告病例。
Antitumor necrosis factor antibodies are widely used in the treatment of autoimmune diseases. We describe the occurrence of autoimmune hepatitis in a patient treated with adalimumab, a fully human IgG antibody against tumor necrosis factor, for psoriatic arthritis. The patient made a full recovery after discontinuation of adalimumab and treatment with steroids. This is the first reported case of adalimumab-induced autoimmune hepatitis.