Obesity and cancer - The update 2013
Obesity and cancer - The update 2013
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DOI：
10.1016/j.beem.2013.04.005
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发表时间：
2013-04-01
影响因子：
7.4
通讯作者：
Boeing, Heiner
中科院分区：
文献类型：
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作者：
Boeing, Heiner
对结直肠癌、乳腺癌、子宫内膜癌、肾细胞癌和食道腺癌过去五年有关“肥胖与癌症”的进展（优先于队列研究）进行了回顾，并与 2008 年回顾的知识进行了比较。新研究大多证实了 5 年前已知的情况。性别似乎在结直肠癌中发挥着重要作用，因为女性因身体肥胖而患结直肠癌的风险远低于男性。成年早期的身体肥胖与肾癌的风险尤其相关，而成年后期的身体肥胖则增加绝经后乳腺癌和子宫内膜癌的风险。脂肪分布对食道腺癌的风险起着重要作用，在较小程度上也对结肠癌的风险起着重要作用。诊断前身体肥胖也在癌症复发和生存中发挥着作用。 (C) 2013 Elsevier Ltd. 保留所有权利。
Progress of the last five years regarding "Obesity and Cancer" with preference to cohort studies was reviewed for cancer of the colorectum, breast, endometrium, renal cell, and adenocarcinomas of the esophagus and compared to the knowledge reviewed in the year 2008. The new studies are mostly confirming what has been known also 5 years ago. Gender seems to play a role in colorectal cancer in that risk due to body fatness is much lower in women than in men. Body fatness at young adulthood is particularly related to risk of renal cancer whereas attained body fatness at a later stage of adulthood is driving the risk for postmenopausal breast and endometrial cancer. Fat distribution is playing a strong role for risk of adenocarcinoma of the esophagus and to a lesser extent also for colon cancer. Prediagnostic body fatness plays also a role in cancer recurrence and survival. (C) 2013 Elsevier Ltd. All rights reserved.