Parathyroid autotransplantation during thyroidectomy - Documentation of graft function
Parathyroid autotransplantation during thyroidectomy - Documentation of graft function
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DOI：
10.1001/archsurg.136.12.1381
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发表时间：
2001-12-01
影响因子：
--
通讯作者：
Tam, SC
中科院分区：
文献类型：
--
作者：
Lo, CY;Tam, SC
假设：可以记录甲状腺切除术期间移植的正常甲状旁腺组织的生化功能。设计：一项干预研究，其中在甲状腺切除术期间将断流或无意中切除的甲状旁腺重新植入前臂肌肉袋中。术后第 1、3、14、28、56 和 84 天，通过双前臂静脉取样评估术后血清甲状旁腺激素水平。地点：三级护理教学医院。患者：7 名接受甲状腺切除术且有术后低钙血症风险的患者。结果：术后第 28 天，所有患者的移植臂和非移植臂之间的甲状旁腺激素测量值存在 1.5 倍的梯度。甲状旁腺激素最大值第56天达到梯度，第84天有6例患者生化功能持续。结论：甲状腺切除术中重新植入的甲状旁腺的生化功能可以得到客观的证明。对于甲状腺手术期间无意中切除或断流的甲状旁腺，应用甲状旁腺自体移植可以保留甲状旁腺功能。
Hypothesis: Biochemical function of normal parathyroid tissue grafted during thyroidectomy can be documented.Design: An intervention study in which devascularized or inadvertently removed parathyroid glands are reimplanted in forearm muscle pockets during thyroidectomy. Postoperative serum parathyroid hormone levels were evaluated by venous sampling from both forearms on postoperative days 1, 3, 14, 28, 56, and 84.Setting: Tertiary care teaching hospital.Patients: Seven patients undergoing thyroidectomy at risk for postoperative hypocalcemia.Results: A 1.5-fold gradient of parathyroid hormone measurements between grafted and nongrafted arms was demonstrated in all patients on postoperative day 28. A maximal parathyroid hormone gradient was reached on day 56, and biochemical function persisted in 6 patients on day 84.Conclusions: Biochemical function of parathyroid glands reimplanted during thyroidectomy can be demonstrated objectively. The application of parathyroid autotransplantation may preserve parathyroid function for inadvertently removed or devascularized parathyroid glands during thyroid surgery.