The frail world of haemodialysis patients in the COVID-19 pandemic era: a systematic scoping review.

The frail world of haemodialysis patients in the COVID-19 pandemic era: a systematic scoping review.
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DOI:
10.1007/s40620-021-01136-5
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发表时间:
2021-10
影响因子:
3.4
通讯作者:
Basile C
Basile C
中科院分区:
医学3区
文献类型:
--
作者:
Alfano G;Ferrari A;Magistroni R;Fontana F;Cappelli G;Basile C

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接受中心血液透析 (HD) 的患者尤其容易遭受 COVID-19 的可怕后果。本系统范围审查旨在确定与 COVID-19 和维持性 HD 相关的文章的程度、范围和性质:它具体报告了 HD 人群中 COVID-19 大流行的流行情况,HD 中心预防、缓解和遏制 COVID-19 大流行的策略的实施情况,人口和临床特征以及儿童和成人 HD 患者的结果。对 2019 年 12 月 1 日至 2021 年 1 月 30 日期间发表的 Pubmed、Scopus、Ovid Medline、Embase 和 Web of Science 中发表的文献进行了多步骤系统检索。两位作者分别筛选了文献的标题和摘要,排除了不相关的文章。对符合纳入标准的论文进行了报告;然后,对纳入文章的特征进行描述性分析并对结果进行叙述性综合。审查过程最终纳入了 145 篇文章。其中大多数都是基于单中心的经验,这些经验自发地形成了最佳实践。大多数研究是在高收入国家(69.7%)进行的,其中一部分(9.6%)不是用英语进行的。透析患者中​​COVID-19的患病率为0%-37.6%。 54% 的纳入文章报告了预防措施,特别强调教育、分诊、卫生和遏制措施。患者经历了一系列不同的症状,导致其中 35%-88.2% 的患者入院。中位住院时间和平均住院时间分别为 8 至 28.5 天和 16.2 至 22 天。各项研究中入住重症监护病房的情况差异很大(从 2.6% 到 70.5%),并且与高死亡率相关(42.8%–100%)。总体而言,0%–47% 的住院患者预后较差。本系统范围审查概述了有关 COVID-19 对脆弱的 HD 患者世界影响的当前知识。此外,它可能有助于实施现有的 COVID-19 预防策略,并提供未满足的需求清单(安全交通、检测、庇护所)。最后,它可能会刺激进行系统评价和荟萃分析,这将构成循证指南的基础。在线版本包含可在 10.1007/s40620-021-01136-5 获取的补充材料。
Patients undergoing in-centre haemodialysis (HD) are particularly exposed to the dire consequences of COVID-19. The present systematic scoping review aims to identify the extent, range, and nature of articles related to COVID-19 and maintenance HD: it reports specifically the prevalence of the COVID-19 pandemic in the HD population, implementation of strategies for the prevention, mitigation and containment of the COVID-19 pandemic in HD centres, demographic and clinical characteristics, and outcomes of the pediatric and adult HD patients. A multi-step systematic search of the literature in Pubmed, Scopus, Ovid Medline, Embase and Web of Science, published between December 1, 2019, and January 30, 2021 was performed. Two authors separately screened the titles and abstracts of the documents and ruled out irrelevant articles. A report of the papers that met inclusion criteria was performed; then, a descriptive analysis of the characteristics of the included articles and a narrative synthesis of the results were performed. The review process ended with the inclusion of 145 articles. Most of them were based on single-centre experiences, which spontaneously developed best practices. Most studies were conducted in high-income countries (69.7%) and a part of them (9.6%) were not in English. Prevalence of COVID-19 among dialysis patients accounted for 0%-37.6%. Preventive measures were reported in 54% of the included articles, with particular emphasis on education, triage, hygiene, and containment measures. Patients experienced a heterogeneous spectrum of symptoms that led 35%-88.2% of them to hospital admission. Median and mean hospital length of stay ranged from 8 to 28.5 and 16.2 to 22 days, respectively. Admission to intensive care units varied widely across studies (from 2.6% to 70.5%) and was associated with high mortality (42.8%–100%). Overall, prognosis was poor in 0%–47% of the hospitalized patients. This systematic scoping review provides an overview of the current knowledge on the impact of COVID-19 on the frail world of HD patients. Furthermore, it may help to implement the existing strategies of COVID-19 prevention and provide a list of unmet needs (safe transport, testing, shelter). Finally, it may be a stimulus for performing systematic reviews and meta-analyses which will form the basis for evidence-based guidelines. The online version contains supplementary material available at 10.1007/s40620-021-01136-5.
DOI: 10.1016/s0140-6736(20)32009-2
发表时间: 2020-10-24
期刊: Lancet (London, England)
影响因子: --
作者:
Anand S;Montez-Rath M;Han J;Bozeman J;Kerschmann R;Beyer P;Parsonnet J;Chertow GM
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发表时间: 2020-05-01
期刊: NEFROLOGIA
影响因子: 2.6
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发表时间: 2020-12-22
期刊: BLOOD PURIFICATION
影响因子: 3
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通讯作者: Maduell, Francisco
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期刊: World journal of nephrology
影响因子: --
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