Self-control depletion and nicotine deprivation as precipitants of smoking cessation failure: A human laboratory model.
Self-control depletion and nicotine deprivation as precipitants of smoking cessation failure: A human laboratory model.
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DOI：
10.1037/ccp0000197
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发表时间：
2017-04
影响因子：
5.9
通讯作者：
Brandon TH
中科院分区：
文献类型：
--
作者：
Heckman BW;MacQueen DA;Marquinez NS;MacKillop J;Bickel WK;Brandon TH
需要了解吸烟复吸的潜在诱因，复吸率高达95%。自我控制强度模型提出，自我控制依赖于有限的资源，容易疲劳，可以提供对复发过程的洞察。目前的研究测试的假设，自我控制耗尽（SCD），从参与情绪抑制，将作为一个新的前因戒烟失败，索引由一个验证的实验室模拟吸烟的失误和复发。我们还检查了SCD效应是否与公认的复发诱发剂（即，尼古丁剥夺）。渴望和行为经济指标（延迟折扣和需求）进行了测试，作为增加戒烟失败的假设机制。最后，一个温和的中介模型被用来测试尼古丁剥夺作为一个假设的调解人SCD的影响。我们采用2 ×2（12小时剥夺与无剥夺; SCD与无SCD）析因受试者间设计（N = 128名吸烟者）。研究的主要假设得到支持，因为SCD增加了失误行为（p = .04）。尼古丁剥夺显着增加渴望，香烟需求，延迟折扣，和失误行为。没有发现SCD对推定的介质的主要影响（即，渴望，需求，折扣），但SCD和剥夺操纵后，渴望（p = 0.04）。适度中介模式具有显著性。SCD被发现增加尼古丁剥夺吸烟者的渴望，这介导了对失效行为的影响。SCD似乎在吸烟复吸中起重要作用，可能是一个可行的干预目标。
The need to understand potential precipitants of smoking relapse is exemplified by relapse rates as high as 95%. The Self-Control Strength model, which proposes that self-control is dependent upon limited resources and susceptible to fatigue, may offer insight into relapse processes. The current study tested the hypothesis that self-control depletion (SCD), produced from engagement in emotional suppression, would serve as a novel antecedent for cessation failure, as indexed by a validated laboratory analogue of smoking lapse and relapse. We also examined whether SCD effects interacted with those of a well-established relapse precipitant (i.e., nicotine deprivation). Craving and behavioral economic indices (delay discounting and demand) were tested as hypothesized mechanisms for increased cessation failure. Ultimately, a moderated mediation model was used to test nicotine deprivation as a hypothesized moderator of SCD effects. We used a 2 ×2 (12-hour deprivation vs. no deprivation; SCD vs. no SCD) factorial between-subjects design (N = 128 smokers). The primary hypothesis of the study was supported, as SCD increased lapse behavior (p = .04). Nicotine deprivation significantly increased craving, cigarette demand, delay discounting, and lapse behavior. No main effects were found for SCD on putative mediators (i.e., craving, demand, discounting), but the SCD and deprivation manipulations interacted upon craving (p = .04). The moderated mediation model was significant. SCD was found to increase craving among nicotine deprived smokers, which mediated effects on lapse behavior. SCD appears to play an important role in smoking relapse and may be a viable target for intervention.