Photoinduced Reduction of Nitroarenes and Tandem C-N Cross-Coupling with Haloarenes
Photoinduced Reduction of Nitroarenes and Tandem C-N Cross-Coupling with Haloarenes
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DOI：
10.1021/acs.orglett.3c03656
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发表时间：
2023-12-04
期刊：
影响因子：
5.2
通讯作者：
Wang, Leifeng
中科院分区：
文献类型：
--
作者：
Bao, Haoshi;Wang, Leifeng
本文报道了以廉价的Ni-（acac）（2）为助催化剂，硝基芳烃和卤代芳烃的C-N交叉偶联反应。该反应被证实为一个分步过程：（1）硝基芳烃的无金属光诱导还原为苯胺衍生物和（2）光催化和镍催化的苯胺与卤代芳烃的C-N交叉偶联。该反应条件简单、温和，可得到高价值的二芳胺，产率高，官能团耐受性好。
An efficient photocatalytic C-N cross-coupling of nitroarenes with haloarenes has been developed using simple and cheap Ni-(acac)(2) as a cocatalyst. The reaction is confirmed as a stepwise process: (1) metal free photoinduced reduction of nitroarenes into aniline derivatives and (2) photo- and Ni-catalyzed C-N cross-coupling of anilines with haloarenes. The reaction conditions are simple and mild, giving high-value diarylamines with good to excellent yields and good functional group tolerance.