ASSESSING CHANGES IN VAGINAL BLEEDING PATTERNS IN CONTRACEPTING WOMEN
ASSESSING CHANGES IN VAGINAL BLEEDING PATTERNS IN CONTRACEPTING WOMEN
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DOI：
10.1016/0010-7824(88)90037-6
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发表时间：
1988-08-01
期刊：
影响因子：
2.9
通讯作者：
DARCANGUES, C
中科院分区：
文献类型：
--
作者：
MACHIN, D;FARLEY, TMM;DARCANGUES, C
在比较替代避孕方法的临床试验中，妇女经常因月经出血模式紊乱而中断。阴道出血日记已被用于监测这些模式，本文提出了两种新的方法来分析这些数据。第一项分析衡量特定模式发生的长期趋势，第二项分析衡量妇女目前的经历与继续使用方法的可能性之间的关系。这些方法之间的对比和参考期的分析方法。使用100和150 mg剂量的长效醋酸甲羟孕酮（DMPA）的相对功效的随机临床试验进行说明。
In clinical trials comparing alternative contraceptive methods, women often discontinue for disturbances in menstrual bleeding patterns. Vaginal bleeding diaries have been used to monitor these patterns, and this paper suggests two new methods of analysis of these data. One analysis measures trends over time in the occurrence of specific patterns and, a second analysis, the relation between a woman''s current experience and the probability of continuing method use. Contrasts between these approaches and the reference period method of analysis are made. a randomized clinical trial of the relative efficacy of 100 and 150 mg doses of depot-medroxyprogesterone acetate (DMPA) is used for illustration.