Could 3D placental volume and perfusion indices measured at 11-14 weeks predict occurrence of preeclampsia in high-risk pregnant women?
Could 3D placental volume and perfusion indices measured at 11-14 weeks predict occurrence of preeclampsia in high-risk pregnant women?
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DOI：
10.3109/14767058.2014.943177
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发表时间：
2015-01-01
影响因子：
1.8
通讯作者：
Youssef, M. A. F. M.
中科院分区：
文献类型：
--
作者：
Hashish, Nawara;Hassan, Ayman;Youssef, M. A. F. M.
目的：子痫前期（PE）是一种已知的导致母亲、胎儿和新生儿发病和死亡的原因。因此，在妊娠11-14周时，结合3D能量多普勒（3DPD）评估胎盘体积和胎盘血流灌注指数对PE高危孕妇的预测价值是一种合适的筛查方法。11-13周时胎盘体积的3D评估和胎盘血管化指数的3DPD评估以及子宫动脉多普勒扫描在这项前瞻性病例对照研究中，在21-22周进行了RI和PI。结果：将100例孕妇分为两组，每组100例。高危组和对照组各50例。高危组和对照组分别有38例（76%）和6.0例（12%）患者发生PE。胎盘体积的平均值（
Objective: Preeclampsia (PE) is a known cause of maternal, fetal and neonatal morbidity and mortality. Thus, evaluation of the predicting value of combining the 3D assessment of placental volume with the assessment of placental perfusion indices through 3D power Doppler (3DPD) at 11-14 weeks in pregnant women at high risk to develop PE could be a suitable screening method.Methods: 3D assessment of placental volume and 3DPD assessment of placental vascularization indices at 11-13 weeks and uterine artery Doppler scan (RI and PI) at 21-22 weeks were conducted in this prospective case-control study. Their predictive ability for PE was assessed.Results: One-hundred pregnant women divided into two groups were enrolled in our study. High-risk group (n = 50) and control group (n = 50). Thirty-eight (76%) patients in the high-risk group and 6.0 (12%) patients in the control group developed PE, respectively. The mean values of placental volume (