THE COMPONENTS OF SYNAPTIC POTENTIALS-EVOKED IN CAT SPINAL MOTO-NEURONS BY IMPULSES IN SINGLE GROUP-IA AFFERENTS
THE COMPONENTS OF SYNAPTIC POTENTIALS-EVOKED IN CAT SPINAL MOTO-NEURONS BY IMPULSES IN SINGLE GROUP-IA AFFERENTS
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DOI：
10.1113/jphysiol.1981.sp013972
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发表时间：
1981-01-01
影响因子：
5.5
通讯作者：
WONG, K
中科院分区：
文献类型：
--
作者：
JACK, JJB;REDMAN, SJ;WONG, K
猫脊髓运动神经元的兴奋性突触后电位（e.p.s.p.）是由 Ia 组传入纤维的脉冲引起的。每个 e.p.s.p. 峰值幅度波动的概率密度。根据记录的峰值幅度和记录噪声的概率密度计算。大多数 e.p.s.p。在不同分量（即特定离散幅度的个体 e.p.s.p.）之间波动，峰值幅度是连续分量之间增量的整数倍。该增量 e.p.s.p 的平均峰值幅度。是.apprx。 e.p.s.p 为 90 .mu.V产生于体细胞或其附近。峰值幅度的概率密度通常不能使用泊松分布或二项式分布来描述。对于许多 e.p.s.p.可以计算每个组件的完整时间过程。这些成分的振幅及其发作潜伏期没有变化。对于一些 e.p.s.p.组件的延迟和时间过程存在差异。 e.p.s.p 的连续分量之间的增量。近端生成的值（在体细胞处）不大于 e.p.s.p 的相应增量。在更远端的树突位点产生。这些结果以及后续论文（Jack、Redman 和 Wong；Hirst、Redman 和 Wong）的结果强化了早期的建议，即每个按钮对于突触后效应都以全有或全无的方式表现，并且同一传入产生的不同按钮的失败概率各不相同。
Excitatory post-synaptic potentials (e.p.s.p.) were evoked in cat spinal motoneurons by impulses in single group Ia afferent fibers. The probability density of the fluctuations in peak amplitude of each e.p.s.p. was calculated from the recorded peak amplitude and the probability density of the recording noise. Most e.p.s.p. fluctuated between different components (i.e., individual e.p.s.p. of a particular discrete amplitude) with peak amplitudes which were integer multiples of the increment between successive components. The average peak amplitude of this incremental e.p.s.p. was .apprx. 90 .mu.V for e.p.s.p. generated at or near the soma. The probability density of the peak amplitude generally could not be described using Poisson or binomial distributions. For many e.p.s.p. the complete time course of each component could be calculated. There was no variability in the amplitude of these components nor in their latency of onset. For some e.p.s.p. there were differences in the latency and time course of the components. The increments between successive components of e.p.s.p. generated proximally were no larger (at the soma) than the corresponding increments for e.p.s.p. generated at more distal dendritic sites. These results and those from subsequent papers (Jack, Redman and Wong; Hirst, Redman and Wong) reinforce earlier suggestions that each bouton behaves in an all-or-nothing manner with respect to post-synaptic effect, and the probability of failure varies at different boutons arising from the same afferent.