Validation of the Hamilton Depression Rating Scale (HDRS) and sociodemographic factors associated with Lebanese depressed patients
Validation of the Hamilton Depression Rating Scale (HDRS) and sociodemographic factors associated with Lebanese depressed patients
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DOI：
10.1016/j.encep.2017.10.010
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发表时间：
2018-11-01
影响因子：
2.7
通讯作者：
Hallit, S.
中科院分区：
文献类型：
--
作者：
Obeid, S.;Hallit, C. Abi Elias;Hallit, S.
目标。 - 汉密尔顿抑郁评定量表 (HDRS) 是评估患者抑郁治疗情况最常用的量表。据我们所知，由于 HDRS 从未在黎巴嫩得到验证，因此我们的主要目标是研究汉密尔顿抑郁量表 (HDRS) 在黎巴嫩抑郁症患者中的相关性、敏感性、特异性以及可靠性和有效性。第二个目标是确定与样本中抑郁症相关的社会人口因素。方法。 - 这项病例对照研究于 2017 年 1 月至 5 月期间进行，纳入了 400 名患者（200 名患者，200 名对照）。结果。 - HDRS 量表项目在四个因素的解决方案上收敛，总共解释了 58.88% 的方差。发现满量程的 Cronbach's alpha 较高 (0.862)。使用HDRS总分作为连续变量的逐步线性回归显示，低社会经济水平、离婚参与者和有精神障碍家族史将分别显着增加HDRS总分（Beta = 4.278；Beta = 5.405；和Beta = 3.922）。然而，具有大学学历会显着降低HDRS总分（Beta = -4.248，P < 0.001）。结论。 - 这项研究表明，阿拉伯语版本的 HDRS 具有良好的心理测量特性，使其成为诊断抑郁症患者的良好工具。绝对有必要在一般实践中识别和治疗抑郁症，以改善患者的治疗结果并减少医疗保健支出。 (C) 2017 L'Encephale，巴黎。
Objectives. - The Hamilton Depression Rating Scale (HDRS) is the most commonly used scale for the evaluation of patients' treatments for depression. Since the HDRS has never been validated in Lebanon to our knowledge, our primary objective, therefore, is to investigate the correlation, sensitivity, specificity, as well as the reliability and the validity of the Hamilton Depression Rating Scale (HDRS) among Lebanese depressed patients. The secondary objective is to identify sociodemographic factors that would be correlated to depression among our sample.Methods. - This case-control study, performed between January till May 2017, included 400 patients (200 patients, 200 controls).Results. - The HDRS scale items converged over a solution of four factors, explaining a total of 58.88% of the variance. A high Cronbach's alpha was found for the full scale (0.862). A stepwise linear regression, using the total HDRS score as continuous variable, showed that a low socioeconomic level, divorced participants and a family history of mental disorders would significantly increase the HDRS total score (Beta = 4.278; Beta = 5.405; and Beta = 3.922) respectively. However, having a university level of education would significantly decrease the HDRS total score (Beta = -4.248, P < 0.001).Conclusion. - This study shows that the Arabic version of the HDRS has promising psychometric properties, making it a good tool to use for the diagnosis of patients with depression. Depression recognition and treatment in general practice with the aim of improving patient outcome and reducing health care expenditure, is definitely warranted. (C) 2017 L'Encephale, Paris.