Scarring Airway Stenosis in Chinese Adults: Characteristics and Interventional Bronchoscopy Treatment.
Scarring Airway Stenosis in Chinese Adults: Characteristics and Interventional Bronchoscopy Treatment.
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DOI：
10.4103/0366-6999.223850
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发表时间：
2018-02-05
影响因子：
6.1
通讯作者：
Wang YL
中科院分区：
文献类型：
--
作者：
Wang T;Zhang J;Qiu XJ;Wang J;Pei YH;Wang YL
由于结核病患病率较高，与其他发达国家相比，疤痕性气道狭窄在中国更为常见。目前国内已广泛采用介入支气管镜治疗治疗该病。本研究揭示了中国成人瘢痕性气道狭窄的特点，并回顾性评价了介入支气管镜治疗该疾病的疗效。纳入2013年1月至2016年6月期间来自18家三级医院的疤痕性气道狭窄患者，分析疤痕性气道狭窄的原因、部位、长度，评价介入支气管镜治疗的疗效。最终研究队列由 392 名患者组成。气管支气管结核（EBTB）是中国成人疤痕性气道狭窄的最常见原因（305/392，77.8%），其中年轻女性的发病率较高。左主支气管最容易受到EBTB的影响，大多数结核后气道疤痕狭窄长度为1.1-2.0 cm。中国患者介入支气管镜治疗疤痕性气道狭窄的平均临床成功率为60.5%。在中国，8.7%的疤痕性气道狭窄患者植入了支架。疤痕性气道狭窄在中国患者中表现出特定的特征。介入支气管镜检查是治疗该疾病有效且安全的方法。
Scarring airway stenosis is commonly seen in China as compared to other developed countries, due to the high prevalence of tuberculosis. Nowadays, interventional bronchoscopy treatment has been widely used to treat this disease in China. This study demonstrated the characteristics of scarring airway stenosis in Chinese adults and retrospectively evaluated the efficacy of interventional bronchoscopy treatment of this disease. Patients with scarring airway stenosis from 18 tertiary hospitals were enrolled between January 2013 and June 2016. The causes, site, and length of scarring airway stenosis were analyzed, and the efficacy of the interventional bronchoscopy treatment was evaluated. The final study cohort consisted of 392 patients. Endotracheobronchial tuberculosis (EBTB) was the most common cause of scarring airway stenosis (305/392, 77.8%) in Chinese adults with a high rate of incidence in young women. The left main bronchus was most susceptible to EBTB, and most posttuberculosis airway scarring stenosis length was 1.1–2.0 cm. The average clinical success rate of interventional bronchoscopy treatment for scarring airway stenosis in Chinese patients is 60.5%. The stent was inserted in 8.7% scarring airway stenosis in China. Scarring airway stenosis exhibits specific characteristics in Chinese patients. Interventional bronchoscopy is a useful and safe treatment method for the disease.