The National Treatment Outcome research study (NTORS): 4-5 year follow-up results

The National Treatment Outcome research study (NTORS): 4-5 year follow-up results
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DOI:
10.1046/j.1360-0443.2003.00296.x
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发表时间:
2003-03-01
期刊:
影响因子:
6
通讯作者:
Kidd, T
Kidd, T
中科院分区:
医学1区
文献类型:
--
作者:
Gossop, M;Marsden, J;Kidd, T

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目的国家治疗结果研究(NTORS)是第一个前瞻性的国家研究药物滥用者之间的治疗结果在英国,NTORS调查结果的药物滥用者在现有的服务,在住宅和社区settings.Design,设置和参与者的研究采用了纵向,前瞻性队列设计。通过结构化访谈收集治疗开始时、1年、2年和4-5年的数据。样本包括418例患者从54个机构和四个治疗models.Measurements采取措施的非法药物使用,注射和共享注射设备,酒精的使用,心理健康和criminal.Findings率的禁欲非法药物增加治疗后的患者从住宅和社区(美沙酮)方案。海洛因、非处方美沙酮、苯二氮卓类药物、注射和共用注射器具的使用频率有所减少。对于大多数变量,1年时降低明显,结局保持在约1年水平或进一步降低。快克可卡因和酒精的结果在4-5年没有显着不同intake.Conclusions大幅减少在一系列的问题行为被发现4-5年后,患者被接纳到国家治疗方案提供日常条件下。大量饮酒和使用快克可卡因的结果不太令人满意,这表明需要修改服务,以更有效地解决这些问题。尽管英国和美国在患者人群和治疗方案方面存在差异,但两国在大规模、多地点研究的结果方面存在许多相似之处。
Aims The National Treatment Outcome Research Study (NTORS) is the first prospective national study of treatment outcome among drug misusers in the United Kingdom, NTORS investigates outcomes for drug misusers treated in existing services in residential and community settings.Design, setting and participants The study used a longitudinal, prospective cohort design. Data were collected by structured interviews at intake to treatment, 1 year, 2 years and at 4-5 years. The sample comprised 418 patients from 54 agencies and four treatment modalities.Measurements Measures were taken of illicit drug use, injecting and sharing injecting equipment, alcohol use, psychological health and crime.Findings Rates of abstinence from illicit drugs increased after treatment among patients from both residential and community (methadone) programmes. Reductions were found for frequency of use of heroin, non-prescribed methadone, benzodiazepines, injecting and sharing of injecting equipment. For most variables, reductions were evident at 1 year with outcomes remaining at about the 1 year level or with further reductions. Crack cocaine and alcohol outcomes at 4-5 years were not significantly different from intake.Conclusions Substantial reductions across a range of problem behaviours were found 4-5 years after patients were admitted to national treatment programmes delivered under day-to-day conditions. The less satisfactory outcomes for heavy drinking and use of crack cocaine suggest the need for services to be modified to tackle these problems more effectively. Despite differences between the United Kingdom and the United States in patient populations and in treatment programmes, there are many similarities between the two countries in outcomes from large-scale, multi-site studies.