A survey of the burden of allergic rhinitis in Europe
A survey of the burden of allergic rhinitis in Europe
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DOI：
10.1111/j.1398-9995.2007.01549.x
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发表时间：
2007-12-01
期刊：
影响因子：
12.4
通讯作者：
Virchow, J. C.
中科院分区：
文献类型：
--
作者：
Canonica, G. W.;Bousquet, J.;Virchow, J. C.
背景资料：在一项前瞻性、横断面、国际性调查中评估了患者和医生对过敏性鼻炎（AR）症状和影响的看法。本文介绍了从五个欧洲国家（德国，法国，意大利，西班牙和英国）的联合调查结果：数据记录了1482例患者和匹配的记录从415个初级保健医生和专家。对1279例（86.3%）患者进行了诊断试验以确认AR。医生和患者都记录了会诊时症状的存在、严重程度和影响，以及经常出现但目前不存在的症状。使用迷你鼻结膜炎生活质量问卷评估健康相关生活质量（HRQoL）。结果：很大一部分患者患有中重度疾病（67.2%; n = 996）、持续性疾病（42.5%; n = 630）和哮喘等合并症（31.5%; n = 467）。总的来说，患者认为他们的疾病比医生更严重（P < 0.001）。在咨询时，三分之一的患者报告说，他们目前的鼻部和眼部症状是中度或重度。根据医生的评估，45.4%（n = 673）和51.3%（n = 760）的患者鼻和眼症状控制良好，18.0%（n = 267）和12.1%（n = 179）的患者症状控制较差。总体而言，43.3%（n = 641）的受访者使用两种或多种药物治疗AR。健康相关的生活质量与疾病严重程度和过去4周内无症状的天数相关。过敏性鼻炎对持续性疾病患者的影响显著大于间歇性疾病患者（2.3 +/- 1.3 vs 1.9 +/- 1.2; P < 0.001）。尽管如此，81.8%（n = 601）的间歇性疾病的患者报告了一些损害他们的日常生活，由于他们的AR。结论：过敏性鼻炎仍然是一个重要的健康问题，因为高负担的症状和它的影响，一般健康和HRQoL的患者咨询这种情况。总体而言，患者和医生在报告疾病严重程度方面的相关性较差。
Background: The perceptions of patients and physicians regarding the symptoms and impact of allergic rhinitis (AR) were assessed in a prospective, cross-sectional, international survey. This paper presents the combined survey results from five European countries (Germany, France, Italy, Spain and the UK).Methods: Data were recorded by 1482 patients and matched with records from 415 primary care physicians and specialists. Diagnostic tests to confirm AR had been performed on 1279 (86.3%) patients. Both physicians and patients recorded the presence, severity and impact of symptoms at the time of consultation in addition to those symptoms frequently, but not currently, present. Health-related quality of life (HRQoL) was assessed using the Mini Rhinoconjunctivitis Quality of Life Questionnaire.Results: A large proportion of patients had moderate-severe disease (67.2%; n = 996), persistent disease (42.5%; n = 630) and comorbidities such as asthma (31.5%; n = 467). Overall, patients rated their disease as more severe than did physicians (P < 0.001). At the time of the consultation, one-third of all patients reported that their current nasal and ocular symptoms were moderate or severe in nature. According to the physicians' assessment, good control of nasal and ocular symptoms was achieved in 45.4% (n = 673) and 51.3% (n = 760) of patients, respectively, and poor symptom control in 18.0% (n = 267) and 12.1% (n = 179). Overall, 43.3% (n = 641) of those surveyed were using two or more medicines for their AR. Health-related quality of life was correlated with disease severity and with the number of days without symptoms in the previous 4 weeks. Allergic rhinitis had a significantly greater impact in patients with more persistent disease than in those with intermittent disease (2.3 +/- 1.3 vs 1.9 +/- 1.2; P < 0.001). Nonetheless, 81.8% (n = 601) of patients with intermittent disease reported some impairment of their daily life as a result of their AR.Conclusions: Allergic rhinitis remains a significant health problem because of the high burden of symptoms and its impact on general well being and HRQoL among patients consulting for this condition. Overall, there was a poor correlation between patients and physicians in the reporting of disease severity.