The Effect of Adverse Childhood Experience on Clinical Diagnosis of a Substance Use Disorder: Results of a Nationally Representative Study
The Effect of Adverse Childhood Experience on Clinical Diagnosis of a Substance Use Disorder: Results of a Nationally Representative Study
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DOI：
10.1080/10826084.2016.1253746
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发表时间：
2017-01-01
影响因子：
2
通讯作者：
Reed, Mark B.
中科院分区：
文献类型：
--
作者：
LeTendre, McKenzie Lynn;Reed, Mark B.
背景资料：药物滥用是与不良童年经历相关的最常见的健康结果之一，并构成重大的公共卫生威胁。目的：本研究的目的是使用全国代表性数据来证明不良童年经历与药物使用障碍之间的关系，并测试宗教是否会调节这种关系。方法：我们使用国家青少年到成人健康纵向研究（n = 11，279）的数据进行了二次分析。三种类型的不良童年经历被认为是：身体，情感和性虐待。Logistic回归用于确定成年后发生酒精使用、大麻使用或其他药物使用障碍的风险是否随着暴露于多种类型不良童年经历的增加而增加，同时控制既往药物使用和其他显示与药物使用相关的人口统计学变量。此外，宗教信仰被调查为不良童年经历和药物滥用之间的关系可能的调解人。结果如下：随着不良童年经历指数得分的增加，在以后的生活中发展为物质使用障碍的可能性也增加。虽然宗教信仰确实显着降低了出现药物使用障碍的可能性，但没有观察到任何缓和作用。结论/重要性：这项研究强调了暴露于童年逆境的长期后果。
Background: Substance abuse is one of the most common health outcomes associated with adverse childhood experience, and poses a significant public health threat. Objectives: The purpose of this study is to demonstrate a relationship between adverse childhood experience and a substance use disorder using nationally representative data as well as to test whether religion moderates this relationship. Methods: We conducted a secondary analysis using data from the National Longitudinal Study of Adolescent to Adult Health (n = 11,279). Three types of adverse childhood experiences were considered; physical, emotional, and sexual abuse. Logistic regression was used to determine whether risk for developing an alcohol use, cannabis use, or other drug use disorder in adulthood increased as exposure to multiple types of adverse childhood experiences increased while controlling for prior substance use and other demographic variables that have shown associations with substance use. In addition, religiosity was investigated as a possible moderator of the relationship between adverse childhood experience and substance abuse. Results: The likelihood of developing a substance use disorder later in life increased as the score on the adverse childhood experience index increased. While religiosity did significantly reduce the likelihood of developing a substance use disorder, no moderating effects were observed. Conclusions/importance: This study underscores the long-term consequences of exposure to childhood adversity.