Health-related quality of life associated with lower urinary tract symptoms in four countries
Health-related quality of life associated with lower urinary tract symptoms in four countries
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DOI：
10.1016/s0090-4295(97)00717-6
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发表时间：
1998-03-01
期刊：
影响因子：
2.1
通讯作者：
Lieber, MM
中科院分区：
文献类型：
--
作者：
Girman, CJ;Jacobsen, SJ;Lieber, MM
目标.描述四个国家通过有效问卷评估与下尿路症状（LUTS）相关的健康相关生活质量（HRQL）。超过6000名男性，招募使用社区或人口为基础的抽样在四个国家，完成问卷调查，征求信息的泌尿系统症状的频率，困扰，干扰程度与日常活动，和其他措施的HRQL.Results.在所有国家，疾病特异性HRQL随着年龄的增长而恶化。调整年龄后，大多数疾病特异性HRQL指标随症状严重程度的增加而显着恶化。症状和HRQL之间的相关性在症状患病率较高的国家（如日本或美国）中最强，在患病率较低的国家（法国，苏格兰）中不太明显，可能反映了评分的变异性较低。老年男性的HRQL指标更差，在所有国家，泌尿系统症状严重程度增加与疾病特异性HRQL更差相关，尽管疾病患病率、药物使用、感知或报告症状或更差HRQL的意愿存在潜在的跨文化差异。这种跨文化的一致性表明，对症状的评估或对日常活动的干扰可能有助于患者的评估。(C)1998年，Elsevier Science Inc. All rights reserved.
Objectives. To describe health-related quality of life (HRQL) associated with lower urinary tract symptoms (LUTS) assessed by validated questionnaires in four countries.Methods. More than 6000 men, recruited by using community-or population-based sampling in four countries, completed questionnaires soliciting information about urinary symptom frequency, bother, degree of interference with daily activities, and other measures of HRQL.Results. In all countries, disease-specific HRQL worsened with increasing age. Adjusting for age, most disease-specific HRQL measures were significantly worse with increasing symptom severity. The correlation between symptoms and HRQL was strongest in countries with higher prevalence of symptoms, such as Japan or the United States, and less pronounced in countries with lower prevalence (France, Scotland), possibly reflecting the lower variability in scores.Conclusions. HRQL measures are worse in older men, and increased urinary symptom severity is associated with worse disease-specific HRQL in all countries, despite potential cross-cultural differences in disease prevalence, medication use, perceptions, or willingness to report symptoms or worse HRQL. This crosscultural consistency suggests that an assessment of symptom bather or interference with daily activities may be useful in patient evaluation. (C) 1998, Elsevier Science Inc. All rights reserved.