Yeast gene expression during growth at low temperature
Yeast gene expression during growth at low temperature
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DOI：
10.1016/s0011-2240(03)00028-2
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发表时间：
2003-06-01
期刊：
影响因子：
2.7
通讯作者：
Komatsu, Y
中科院分区：
文献类型：
--
作者：
Homma, T;Iwahashi, H;Komatsu, Y
利用基因芯片技术研究了酿酒酵母低温生长过程中的基因表达。相对于25 ℃，大量基因在4 ℃时表达增加或减少。虽然没有进行温度转换，但观察到冷休克基因TIP1、TIR1、TIR2和NSR1的差异表达。这些基因可能是在低至摄氏4度的温度下生长以及适应温度迅速下降所必需的。发现一类新的基因，许多功能未知，在低温下生长过程中被诱导。我们建议称这些基因为“低温生长基因”。“（C）2003 Elsevier Science（USA），版权所有。
Gene expression during growth at low temperature in the yeast Saccharomyces cerevisiae was investigated by means of DNA microarray analysis. A large number of genes showed an increase or decrease in expression at 4degreesC relative to 25degreesC. Although a temperature shift was not performed, differential expression of the cold shock genes TIP1, TIR1, TIR2, and NSR1 was observed. These genes may be necessary for growth at temperatures as low as 4degreesC as well as for adapting to rapid drops in temperature. A new class of genes, many with unknown functions, was found to be induced during growth at low temperature. We propose to call these genes "low temperature growth genes." (C) 2003 Elsevier Science (USA), All rights reserved.