Gender and urban-rural influences on antibiotic purchasing and prescription use in retail drug shops: a one health study.
Gender and urban-rural influences on antibiotic purchasing and prescription use in retail drug shops: a one health study.
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DOI：
10.1186/s12889-023-15155-3
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发表时间：
2023-02-02
影响因子：
4.5
通讯作者：
中科院分区：
文献类型：
--
作者：
很少有研究报告低收入和中等收入国家（LMIC）从零售药店购买抗生素与性别有关。使用一个健康的方法，我们的目的是检查性别层面的人类和动物的抗生素购买和使用处方的零售药店在孟加拉国。我们在一个农村和一个城市地区的20家药店进行了顾客观察。顾客性别，抗生素购买和处方使用记录在4小时的观察（2个会议2小时），在每个商店。我们包括销售人用药物的药店（n = 15）;动物药物（n = 3），以及销售人用药物和动物药物的商店（n = 2）。在582次观察中，31.6%的药店顾客是妇女。妇女几乎占城市药店顾客的一半（47.1%），但在农村药店顾客中仅占17.2%（p < 0.001）。抗生素购买在城市商店比农村商店更常见（占所有交易的21.6%比12.2%，p = 0.003）。只有四分之一（26.0%）购买抗生素的客户使用处方。女性比男性更可能使用抗生素处方（比值比（OR）= 4.04，95% CI 1.55，10.55），城市比农村客户更可能使用抗生素处方（OR = 4.31，95% CI 1.34，13.84）。在调整城乡地区后，女性仍然比男性更有可能使用处方（调整后的OR = 3.38，95% CI 1.26，9.09），但这部分是由于男性在没有处方的情况下为动物购买抗生素。销售动物药的药店的顾客使用抗生素处方的比例最低（占抗生素购买量的4.8%）。这项研究发现，近四分之三的抗生素销售是没有处方的，包括对人类医学至关重要的抗菌药物清单上的抗生素。与妇女相比，去药店的男子更有可能在没有处方的情况下购买抗生素，而农村药店的女性顾客人数不足。社区的抗生素管理举措需要考虑到药店对人类和动物医学抗生素的使用和处方使用的性别和城乡层面。这些举措可以加强国家行动计划。在线版本包含补充材料，可通过10.1186/s12889-023-15155-3获得。
Few studies have reported antibiotic purchases from retail drug shops in relation to gender in low and middle-income countries (LMICs). Using a One Health approach, we aimed to examine gender dimensions of antibiotic purchases for humans and animals and use of prescriptions in retail drug shops in Bangladesh. We conducted customer observations in 20 drug shops in one rural and one urban area. Customer gender, antibiotic purchases, and prescription use were recorded during a four-hour observation (2 sessions of 2 hours) in each shop. We included drug shops selling human medicine (n = 15); animal medicine (n = 3), and shops selling both human and animal medicine (n = 2). Of 582 observations, 31.6% of drug shop customers were women. Women comprised almost half of customers (47.1%) in urban drug shops but only 17.2% of customers in rural drug shops (p < 0.001). Antibiotic purchases were more common in urban than rural shops (21.6% versus 12.2% of all transactions, p = 0.003). Only a quarter (26.0%) of customers who purchased antibiotics used a prescription. Prescription use for antibiotics was more likely among women than men (odds ratio (OR) = 4.04, 95% CI 1.55, 10.55) and more likely among urban compared to rural customers (OR = 4.31 95% CI 1.34, 13.84). After adjusting for urban-rural locality, women remained more likely to use a prescription than men (adjusted OR = 3.38, 95% CI 1.26, 9.09) but this was in part due to antibiotics bought by men for animals without prescription. Customers in drug shops selling animal medicine had the lowest use of prescriptions for antibiotics (4.8% of antibiotic purchases). This study found that nearly three-quarters of all antibiotics sold were without prescription, including antibiotics on the list of critically important antimicrobials for human medicine. Men attending drug shops were more likely to purchase antibiotics without a prescription compared to women, while women customers were underrepresented in rural drug shops. Antibiotic stewardship initiatives in the community need to consider gender and urban-rural dimensions of drug shop uptake and prescription use for antibiotics in both human and animal medicine. Such initiatives could strengthen National Action Plans. The online version contains supplementary material available at 10.1186/s12889-023-15155-3.
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影响因子：
4.6
作者：
Rahman MS;Yoshida N;Tsuboi H;Karmoker JR;Kabir N;Schaefermann S;Akimoto Y;Bhuiyan MA;Reza MS;Kimura K
通讯作者：
Kimura K
影响因子：
8.1
作者：
Dasari M;David SD;Miller E;Puyana JC;Roy N
通讯作者：
Roy N
影响因子：
168.9
作者：
Laxminarayan, Ramanan;Matsoso, Precious;Davies, Sally
通讯作者：
Davies, Sally
DOI：
10.1016/s2214-109x(21)00024-3
发表时间：
2021-05
期刊：
The Lancet. Global health
影响因子：
--
作者：
Do NTT;Vu HTL;Nguyen CTK;Punpuing S;Khan WA;Gyapong M;Asante KP;Munguambe K;Gómez-Olivé FX;John-Langba J;Tran TK;Sunpuwan M;Sevene E;Nguyen HH;Ho PD;Matin MA;Ahmed S;Karim MM;Cambaco O;Afari-Asiedu S;Boamah-Kaali E;Abdulai MA;Williams J;Asiamah S;Amankwah G;Agyekum MP;Wagner F;Ariana P;Sigauque B;Tollman S;van Doorn HR;Sankoh O;Kinsman J;Wertheim HFL
通讯作者：
Wertheim HFL
影响因子：
5.4
作者：
Saradamma, RD;Higginbotham, N;Nichter, M
通讯作者：
Nichter, M