Fronto-parieto-cerebellar interaction associated with intermanual transfer of monkey tool-use learning
Fronto-parieto-cerebellar interaction associated with intermanual transfer of monkey tool-use learning
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DOI：
10.1016/s0304-3940(02)01477-5
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发表时间：
2003-03-20
影响因子：
2.5
通讯作者：
Iriki, A
中科院分区：
文献类型：
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作者：
Obayashi, S;Suhara, T;Iriki, A
用一只手（原始手; OH）进行的先前运动技能学习（原始学习; OL）可以影响用另一只手（转移手; TH）进行的相同技能的再学习（转移学习; TL）。这种现象被称为学习的手间迁移。我们通过正电子发射断层扫描测量两只猴子的局部脑血流量，探索了双手之间使用工具的大脑激活的专门化。我们发现，在双侧前额叶皮层，双侧顶内沟区，和小脑对侧TH的TL指定的大脑激活。结果表明，这些区域可能与工具使用学习的手间转移有关，大概是在修改OH特定的运动记忆痕迹方面。(C)2003爱思唯尔科学爱尔兰有限公司保留所有权利。
Prior motor skill learning (original learning; OL) with one hand (original hand; OH) can affect relearning of the same skill (transfer learning; TL) with the opposite hand (transferred hand; TH). This phenomenon is known as intermanual transfer of learning. We explored specialization of brain activation underlying tool-use between hands by measuring regional cerebral blood flow in two monkeys using positron emission tomography. We found brain activation specified for TL in the bilateral prefrontal cortex, bilateral intraparietal sulcus region, and cerebellum contralateral to TH. The results suggest that those regions may be related to intermanual transfer of tool-use learning, presumably in terms of modifying a motor engram specific for OH. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.