EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure
EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure
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DOI：
10.1016/j.jhep.2016.12.003
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发表时间：
2017-05-01
影响因子：
25.7
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中科院分区：
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急性肝功能衰竭（ALF）这个术语经常被用作描述出现或发展为急性肝功能障碍的患者的通用表达。然而，在肝病学实践的背景下，ALF指的是一种高度特异性和罕见的综合征，其特征是在没有潜在慢性肝病的个体中出现肝脏血液检查的急性异常。该疾病的发展过程与肝脏凝血功能障碍的病因有关，并与肝性脑病引起的临床明显的意识水平改变有关。当病人前来就医时，有几个重要的措施是立即必要的。这些，以及额外的临床程序将是这些临床实践指南的主题。(C) 2016欧洲肝脏研究协会。Elsevier B.V.版权所有。
The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. In the context of hepatological practice, however, ALF refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. The disease process is associated with development of a coagulopathy of liver aetiology, and clinically apparent altered level of consciousness due to hepatic encephalopathy. Several important measures are immediately necessary when the patient presents for medical attention. These, as well as additional clinical procedures will be the subject of these clinical practice guidelines. (C) 2016 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.