Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis.
Distinct vascular patterns of early synovitis in psoriatic, reactive, and rheumatoid arthritis.
复制标题
DOI：
10.1002/1529-0131(199907)42:7
复制
发表时间：
1999-07
影响因子：
--
通讯作者：
R. Reece;J. Cañete;W. Parsons;P. Emery;D. Veale
中科院分区：
文献类型：
--
作者：
R. Reece;J. Cañete;W. Parsons;P. Emery;D. Veale
目的 检查银屑病关节炎 (PsA)、反应性关节炎 (ReA) 和类风湿性关节炎 (RA) 早期滑膜炎的宏观血管模式，并评估滑膜炎分级特征的可靠性。方法 对 44 名接受关节镜检查的膝关节滑膜炎患者（14 名 PsA、12 名 ReA 和 18 名 RA）进行了评估。检查的视频记录由 3 名关节镜医师独立评分，他们对患者的身份和临床细节不知情。记录血管分布、绒毛形成、血管翳、颗粒度和毛细血管充血的特征，并记录血管分布、绒毛肥厚和血管翳特征的kappa值（-1或=0.8）。 73% 的 PsA 和 ReA 患者的血管主要是曲折、浓密的； 89% 的 RA 患者的血管主要是直的、分支的。结论 与 RA 相比，PsA 和 ReA 的不同血管模式可能反映了这些关节炎发病机制中不同的特定血管因素。血管分布和绒毛肥大是滑膜炎分级最可靠的特征。
OBJECTIVE To examine the macroscopic vascular pattern of early synovitis in psoriatic arthritis (PsA), reactive arthritis (ReA), and rheumatoid arthritis (RA) and to assess the reliability of the grading features for synovitis. METHODS Forty-four patients (14 PsA, 12 ReA, and 18 RA) with knee synovitis who were undergoing arthroscopy were assessed. Video recordings of the examination were scored independently by 3 arthroscopists who were blinded to the patient's identity and clinical details. Features of vascularity, villous formation, pannus, granularity, and capillary hyperemia were recorded and kappa values (-1 or =0.8) for features of vascularity, villous hypertrophy, and pannus. Seventy-three percent of the PsA and ReA patients had predominantly tortuous, bushy vessels; 89% of the RA patients had mainly straight, branching vessels. CONCLUSION The distinct vascular patterns in PsA and ReA compared with those in RA may reflect different specific vascular factors in the pathogenesis of these arthritides. Vascularity and villous hypertrophy are the most reliable features of synovitis grading.