Study on the organoleptic intensity scale for measuring oral malodor

Study on the organoleptic intensity scale for measuring oral malodor
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DOI:
10.1177/154405910408300116
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发表时间:
2004-01-01
影响因子:
7.6
通讯作者:
El-Maaytah, M
El-Maaytah, M
中科院分区:
医学1区
文献类型:
--
作者:
Greenman, J;Duffield, J;El-Maaytah, M

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0-5感官量表广泛用于呼吸研究和测试除臭剂的功效。然而,气味分数和目标气味剂的气体浓度之间的精确关系是未知的。本研究的目的是从气味法官(n=7)的纯气味(n=8)的口腔恶臭中发现的代表性的平均感官评分。法官使用一个共同的0-5规模报告的气味强度的样本集的浓度随机顺序。数据的回归分析表明,气味得分是成正比的气味剂的对数浓度,和斜率的比较表明H2S是最显着的气味功率。检测阈值(mol.dm(-3))为:臭素(7.2x10(-13))<甲基苯丙胺(1.0x10(-11))<三甲胺(1.8x10(-11))<异戊酸(1.8 × 10(-11))<丁酸盐(2.3 × 10(-10))<硫化氢(6.4 × 10(-10))<腐胺(9.1 × 10(-10))<二甲基二硫化物(5.9 × 10(-8))。该研究证明了嗅觉反应的指数性质,并表明任何单一化合物对恶臭的贡献除了浓度外还取决于气味功率和阈值。
The 0-5 organoleptic scale is used widely in breath research and in trials to measure the efficacy of anti-odor agents. However, the precise relationship between odor scores and gas concentrations of target odorants is unknown. The purpose of this study was to relate mean organoleptic scores from odor judges (n=7) for pure odorants (n=8) representative of those found in oral malodor. Judges used a common 0-5 scale to report the odor intensity of sample sets in random order of concentration. Regression analysis of data showed that odor score was proportional to the log concentration of odorant, and comparison of slopes showed H2S to be the most significant in terms of odor power. Detection thresholds (mol.dm(-3)) were: Skatole (7.2x10(-13)) < methylmercaptan (1.0x10(-11)) < trimethylamine (1.8x10(-11)) < isovalerate (1.8x10(-11)) < butyrate (2.3x10(-10)) < hydrogen sulphide (6.4x10(-10)) < putrescine (9.1x10(-10)) < dimethyl disulphide (5.9x10(-8)). The study demonstrates the exponential nature of the olfactory response and shows that any single compound's contribution to malodor depends on odor power and threshold in addition to concentration.