Dynamic Contact Angle Analysis of Silicone Hydrogel Contact Lenses
Dynamic Contact Angle Analysis of Silicone Hydrogel Contact Lenses
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DOI：
10.1177/0885328210363505
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发表时间：
2011-07-01
影响因子：
2.9
通讯作者：
Maldonado-Codina, Carole
中科院分区：
文献类型：
--
作者：
Read, Michael Leonard;Morgan, Philip Bruce;Maldonado-Codina, Carole
接触角测量用于推断接触镜的临床润湿特性。自从引入硅水凝胶接触透镜材料以来，这种表征变得更加普遍，由于包含含正己烷的组分，硅水凝胶接触镜片材料与体内润湿性降低有关。使用一致的方法和单个研究者，采用动态捕获气泡技术（采用定制的全自动图像分析）测量了11种市售硅水凝胶接触透镜类型的前进和后退接触角。发现前进接触角的范围在20度和72度之间，镜片分为六个统计学上离散的组。后退接触角落在一个较窄的范围内，在17度和22度之间，镜片分为三组。这些实验室测量值与晶状体临床性能之间的关系需要进一步研究。
Contact angle measurements are used to infer the clinical wetting characteristics of contact lenses. Such characterization has become more commonplace since the introduction of silicone hydrogel contact lens materials, which have been associated with reduced in vivo wetting due to the inclusion of siloxane-containing components. Using consistent methodology and a single investigator, advancing and receding contact angles were measured for 11 commercially available silicone hydrogel contact lens types with a dynamic captive bubble technique employing customized, fully automated image analysis. Advancing contact angles were found to range between 20 degrees and 72 degrees with the lenses falling into six statistically discrete groupings. Receding contact angles fell within a narrower range, between 17 degrees and 22 degrees, with the lenses segregated into three groups. The relationship between these laboratory measurements and the clinical performance of the lenses requires further investigation.