THE INTERGENERATIONAL RELATIONSHIP BETWEEN MOTHERS BIRTH-WEIGHT, INFANT BIRTH-WEIGHT AND INFANT-MORTALITY IN BLACK-AND-WHITE MOTHERS

THE INTERGENERATIONAL RELATIONSHIP BETWEEN MOTHERS BIRTH-WEIGHT, INFANT BIRTH-WEIGHT AND INFANT-MORTALITY IN BLACK-AND-WHITE MOTHERS
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DOI:
10.1111/j.1365-3016.1995.tb00162.x
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发表时间:
1995-10-01
影响因子:
2.8
通讯作者:
HOLT, VL
HOLT, VL
中科院分区:
医学3区
文献类型:
--
作者:
SANDERSON, M;EMANUEL, I;HOLT, VL

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利用1988年全国母婴健康调查研究了白色和黑人母亲的出生体重与其婴儿结局之间的关系。本身出生体重低的白色和黑人妇女分娩极低出生体重儿(VLBW)、中度低出生体重儿(MLBW)、极早产儿和小于胎龄儿(SGA)的风险增加。调整孕前体重和身高的混杂效应后,所有这些结果的风险都略有降低,而白色母亲中与母亲出生体重相关的中度低出生体重的风险则显著降低。在白色母亲中,母亲出生体重对婴儿出生体重特异性婴儿死亡率的影响很小;然而,出生时体重低于4磅的黑人母亲分娩正常出生体重婴儿随后死亡的风险显著增加。虽然与低出生体重相关的各种结局的风险在黑人母亲中并不总是高于白色母亲,但调整孕前体重和身高对白色母亲的影响大于黑人母亲。我们建议,干预措施,以减少与低产妇出生体重相关的不良妊娠结局的风险,应试图优化孕前体重,促进儿童的健康和成长。
The relationship between the birthweight of white and black mothers and the outcomes of their infants were examined using the 1988 National Maternal and Infant Health Survey. White and black women who were low birthweight themselves were at increased risk of delivering very low birthweight (VLBW), moderately low birthweight (MLBW), extremely preterm and small size for gestational age (SGA) infants. Adjustment for the confounding effects of prepregnant weight and height reduced the risks of all these outcomes slightly, and more substantially reduced the maternal birthweight associated risk of moderately low birthweight among white mothers. There was little effect of maternal birthweight on infant birthweight-specific infant mortality in white mothers; however, black mothers who weighed less than 4 lbs at birth were at significantly increased risk of delivering a normal birthweight infant who subsequently died. Although the risks for the various outcomes associated with low maternal birthweight were not consistently higher in black mothers compared with white mothers, adjustment for prepregnant weight and height had a greater effect in white mothers than in black mothers. We suggest that interventions to reduce the risks for adverse pregnancy outcomes associated with low maternal birthweight should attempt to optimise prepregnant weight and foster child health and growth.