Increasing the generalizability of economic evaluations: Recommendations for the design, analysis, and reporting of studies
Increasing the generalizability of economic evaluations: Recommendations for the design, analysis, and reporting of studies
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DOI：
10.1017/s0266462305050221
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发表时间：
2005-03-01
影响因子：
3.2
通讯作者：
Sculpher, M
中科院分区：
文献类型：
--
作者：
Drummond, M;Manca, A;Sculpher, M
目的：卫生技术评估（HTA）日益成为一项国际活动，卫生技术评估机构相互合作以避免不必要的重复工作。然而，分享卫生技术评估的结果引起了关于其普遍性的问题;也就是说，在一个国家进行的卫生技术评估的结果是否与另一个国家相关？方法：本研究提出了提高经济评价的普遍性的建议。它们代表了HTAs的重要组成部分，通常被认为具有有限的概括性。结果：建议使用患者水平的数据（即，与临床试验一起进行的评估）和使用决策分析模型的研究。结论：如果实施，建议将增加卫生技术评估投资的价值。
Objectives: Health technology assessment (HTA) is increasingly an international activity, and HTA agencies collaborate to avoid unnecessary duplication of effort. However, the sharing of the results from HTAs raises questions about their generalizability; namely, are the results of an HTA undertaken in one country relevant to another?Methods: This study presents recommendations for increasing the generalizability of economic evaluations. They represent an important component of HTAs and are commonly thought to have limited generalizability.Results: Recommendations are given for studies using patient-level data (i.e., evaluations conducted alongside clinical trials) and for studies using decision analytic modeling.Conclusions: If implemented, the recommendations would increase the value for investments in HTA.