Synaptic interactions between GABAergic neurons and trigeminothalamic cells in the rat trigeminal nucleus caudalis.
Synaptic interactions between GABAergic neurons and trigeminothalamic cells in the rat trigeminal nucleus caudalis.
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大鼠三叉神经尾核中 GABA 能神经元和三叉丘脑细胞之间的突触相互作用。
DOI：
10.1002/syn.890060408
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Aronin,N
中科院分区：
文献类型：
--
作者：
DiFiglia,M;Aronin,N
用GABA免疫组织化学和三叉神经丘脑通路逆行WGA-HRP标记相结合的方法，研究了三叉神经尾侧核内GABA能神经元与丘脑投射细胞之间的突触相互作用。结果表明，GABA阳性神经元和投射细胞在三叉神经脊束核内相互独立，但紧密融合。GABA能轴突终末与三叉神经丘脑神经元的胞体和树突形成对称性突触联系。反过来，一些充满WGA-HRP的轴突终末可能起源于投射神经元的轴突侧支，与含有GABA的神经元形成突触联系。结果提示，在三叉神经脊束核内，GABA神经元与三叉神经丘脑细胞之间存在相互调制。
Synaptic interactions between GABAergic neurons and thalamic projecting cells within the trigeminal nucleus caudalis were examined using a combined method of GABA immunohistochemistry and retrograde WGA‐HRP labeling of the trigeminothalamic pathway. Results showed that GABA‐positive neurons and projecting cells were separate but closely intermingled within the spinal trigeminal nucleus. GABAergic axon terminals formed symmetric synaptic connections with the cell bodies and dendrites of trigeminothalamic neurons. In turn, some WGA‐HRP filled axon terminals, presumed to originate from axon collaterals of the projecting neurons, formed synaptic connections with GABA containing neurons. The results suggest that in the spinal trigeminal nucleus there is a reciprocal modulation between GABA neurons and trigeminothalamic cells.