Associations between pathogens in healthy pigs and pigs with pneumonia
Associations between pathogens in healthy pigs and pigs with pneumonia
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DOI：
10.1136/vr.162.9.267
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发表时间：
2008-03-01
影响因子：
2.2
通讯作者：
Heinritzi, K.
中科院分区：
文献类型：
--
作者：
Palzer, A.;Ritzmann, M.;Heinritzi, K.
本研究的目的是评估不同病原体在猪肺炎和支气管肺炎发展中的相关性。对来自100头无临床体征的猪和239头有呼吸道疾病临床体征的猪的支气管肺泡灌洗液样品进行了猪肺炎支原体、猪鼻支原体、US型猪呼吸和生殖综合征病毒（PRRSV）、EU型PRRSV、猪圆环病毒2型（PCV-2）、A型流感病毒、α-溶血性链球菌属、β-溶血性链球菌属、多杀性后杆菌、支气管败血波氏杆菌、副猪嗜血杆菌和胸膜肺炎放射杆菌。这些潜在的病原体在有呼吸问题的猪中比在没有临床症状的猪中更频繁地被检测到。PCV-2和α-溶血性链球菌是最常检测到的病原体;仅在两例病例中分离出胸膜肺炎。与健康猪相比，猪中的微生物与临床体征之间的关联更频繁。特别是，α-溶血性链球菌和猪肺炎支原体均与猪鼻支原体、EU型PRRSV、多杀性巴斯德菌和支气管炎B型菌的存在相关，并且α-溶血性链球菌也更常发生在已感染其他病原体的猪中。多杀性P和B支气管败血症与猪肺炎支原体、α-溶血性链球菌、EU型和US型PRRSV均显著相关。
The aim of this study was to evaluate the associations between different pathogens in the development of pneumonia and bronchopneumonia in pigs. Samples of bronchoalveolar lavage fluid from 100 pigs showing no clinical signs and 239 pigs with clinical signs of respiratory disease were examined for Mycoplasma hyopneumoniae, Mycoplasma hyorhinis, US-type porcine respiratory and reproductive syndrome virus (PRRSV), EU-type PRRSV, porcine circovirus type 2 (PCV-2), influenza virus type A, alpha-haemolytic Streptococcus species, beta-haemolytic Streptococcus species, Posteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis and Actinobacillus pleuropneumaniae. These potential pathogens were detected more frequently in the pigs with respiratory problems than in the pigs with no clinical signs. PCV-2 and alpha-haemolytic streptococci were the pathogens most frequently detected; A pleuropneumoniae was isolated in only two cases. There were more often associations between the organisms in the pigs with clinical signs than in the healthy pigs. in particular, alpha-haemolytic streptococci and M hyopneumoniae were both associated with the presence of M hyorhinis, EU-type PRRSV, P multocida and B bronchiseptica, and alpha-haemolytic streptococci also occurred more often in pigs that were already infected with other pathogens. P multocida and B bronchiseptica were both significantly associated with M hyopneumoniae, alpha-haemolytic streptococci, EU-type PRRSV and US-type PRRSV.