Biomedical simulation of heat transfer in a human heart

Biomedical simulation of heat transfer in a human heart
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DOI:
10.1021/ci050206p
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发表时间:
2005-11-01
影响因子:
5.6
通讯作者:
Trobec, R
Trobec, R
中科院分区:
化学2区
文献类型:
--
作者:
Sterk, M;Trobec, R

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本文介绍了医学领域传热数值模拟的理论和实践经验。以手术期间人类心脏的冷却为例。从构建不规则形状的 3 维模型开始描述模拟过程的所有阶段。该数学模型基于扩散和纳维-斯托克斯方程。使用显式时间步进方案通过有限差分近似求解偏微分方程组,以获得完整模拟区间(通常为 I h)的解的时间演化。一个典型的域由数百万个体素组成;因此,该程序被并行化以加速模拟。在 Linux 集群中的 16 个处理器上获得了 8.2 的加速比。
Theory and practical experiences from numerical simulations of heat transfer in the field of medicine are presented in this paper. The cooling of a human heart during surgery was taken as an illustrative example. All phases of the simulation process are described starting with the construction of an irregularly shaped 3-dimensional model. The mathematical model is based on diffusion and Navier-Stokes equations. The system of partial differential equations is solved by finite difference approximation using an explicit time-stepping scheme to obtain the time evolution of the solution for the complete simulated interval, which is typically I h. A typical domain is composed of several million voxels; therefore, the program was parallelized to speed up the simulation. A speed-up of 8.2 was obtained on 16 processors in a Linux cluster.