IRON METABOLISM IN PREMATURE INFANTS .1. ABSORPTION AND UTILIZATION OF IRON AS MEASURED BY ISOTOPE STUDIES
IRON METABOLISM IN PREMATURE INFANTS .1. ABSORPTION AND UTILIZATION OF IRON AS MEASURED BY ISOTOPE STUDIES
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DOI：
10.1016/s0022-3476(63)80185-7
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发表时间：
1963-01-01
影响因子：
5.1
通讯作者：
WORKMAN, JB
中科院分区：
文献类型：
--
作者：
GORTEN, MK;HEPNER, R;WORKMAN, JB
对14例1 ~ 10周龄健康早产儿给予1 μc Fe ~（59）后，分析其铁吸收率和利用率。标记铁的吸收和增长率之间的显着相关性被证明。通过内脏表面计数和血液采样追踪吸收同位素铁的过程。用于血红蛋白形成的示踪铁的量与生长速率显著相关。红细胞生成活性的程度似乎对吸收的铁的直接利用有积极的影响。早产儿在出生后的前10周比婴儿期和儿童期吸收和利用铁的程度更高。
Data from study of 14 well and healthy premature infants, 1 to 10 weeks old given1 μc of Fe59, were analyzed for percentage absorption and utilization of iron. A significant correlation between tagged iron absorption and rate of growth was demonstrated. The course of absorbed isotopic iron was traced by surface counting of internal organs and blood sampling. The amount of tracer iron utilized for hemoglobin formation correlated significantly with rate of growth. The degree of erythropoietic activity appears to affect positively the immediate utilization of absorbed iron. Premature infants absorb and utilize iron to a greater degree during the first 10 weeks of life than in later infancy and childhood.