Monoclonal antibodies to three non-glycosylated antigens of herpes simplex virus type 2.
Monoclonal antibodies to three non-glycosylated antigens of herpes simplex virus type 2.
复制标题
针对 2 型单纯疱疹病毒的三种非糖基化抗原的单克隆抗体。
DOI：
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发表时间：
1982
影响因子：
3.8
通讯作者：
A. Minson
中科院分区：
文献类型：
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作者：
C. McLean;A. Buckmaster;D. Hancock;A. Buchan;A. Fuller;A. Minson
总结
描述了三种单克隆抗体的生产和性质，命名为LP 1，LP 4和AP 2，针对单纯疱疹病毒2型的非糖基化多肽。LP 1对多肽VP 16具有特异性，并与HSV-1交叉反应; LP 4与主要的DNA结合蛋白反应，并具有类型特异性。AP 2针对HSV-1和HSV-2的主要衣壳抗原。
Summary
The production and properties of three monoclonal antibodies, designated LP1, LP4 and AP2, directed against non-glycosylated polypeptides of herpes simplex virus type 2 are described. LP1 is specific for polypeptide VP16 and cross-reacts with HSV-1; LP4 reacts with the major DNA-binding protein and is type-specific. AP2 is directed against the major capsid antigen of HSV-1 and HSV-2.