Heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia
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DOI：
10.1056/nejmcp052967
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发表时间：
2006-08-24
影响因子：
158.5
通讯作者：
Ortel, Thomas L.
中科院分区：
文献类型：
--
作者：
Arepally, Gowthami M.;Ortel, Thomas L.
一名 63 岁男性患有冠状动脉疾病，最近接受了搭桥手术，出现呼吸困难。实验室检测显示，血小板计数为每立方毫米 86,000 个，而九天前出院时为每立方毫米 225,000 个。胸部X光检查结果无异常；胸部螺旋计算机断层扫描显示肺栓塞。怀疑是肝素诱导的血小板减少症。需要进行哪些诊断研究？该患者应如何治疗？
A 63-year-old man with coronary artery disease who has recently undergone bypass surgery presents with dyspnea. Laboratory testing reveals a platelet count of 86,000 per cubic millimeter, as compared with 225,000 per cubic millimeter at the time of discharge nine days earlier. Findings on chest radiography are unremarkable; spiral computed tomography of the chest shows a pulmonary embolism. Heparin-induced thrombocytopenia is suspected. What diagnostic studies are warranted, and how should this patient be treated?