The longitudinal relationship between loneliness, social isolation, and frailty in older adults in England: a prospective analysis
The longitudinal relationship between loneliness, social isolation, and frailty in older adults in England: a prospective analysis
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DOI：
10.1016/s2666-7568(20)30038-6
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发表时间：
2021-02-03
影响因子：
13.1
通讯作者：
Pendleton, Neil
中科院分区：
文献类型：
--
作者：
Davies, Katie;Maharani, Asri;Pendleton, Neil
据估计，65岁及以上的人中约有10%是体弱的。孤独和社会孤立与死亡率增加和功能能力下降有关。我们评估了脆弱状态的趋势与孤独和社会隔离超过14年的一个有代表性的样本，在这个纵向研究中，我们使用的数据从英国的老龄化纵向研究（艾尔莎），这是旨在招募一个有代表性的样本，年龄在50岁及以上的成年人生活在英国的私人家庭。我们分析了Waves 2-8（涵盖2004年6月至2017年6月）。使用虚弱指数定义虚弱，连续分析并作为预先指定的类别，将个体分类为非虚弱（0.08至= 0.25至1.00）。使用加州大学洛杉矶分校3项孤独量表测量孤独感，并按照之前的艾尔莎方法测量社会孤立感，两组评分均分为低、中或高。线性混合的方法和考克斯比例风险模型，调整confers.Findings-研究样本包括9171参与者在基线波2（4083男性和5088女性），在随后的波类似的数字。在固定效应模型中，调整了婚姻状况、年龄、性别、财富和吸烟状况，孤独感水平较高的受访者有较高的脆弱指数得分（β系数0.006，95% CI 0.006至0.007; p
Background It is estimated that about 10% of people aged 65 and older are frail. Loneliness and social isolation are linked to increased mortality and poorer functional capacity. We assessed trends in frailty status associated with loneliness and social isolation over 14 years in a representative sample of English older adults.Methods In this longitudinal study, we used data from the English Longitudinal Study of Ageing (ELSA), which was designed to recruit a representative sample of adults aged 50 years and older living in private households in England. We analysed Waves 2-8 (covering June, 2004, to June, 2017). Frailty was defined using the frailty index, analysed continuously and as pre-specified categories, to categorise individuals as being non-frail (0.08 to = 0.25 to 1.00). Loneliness was measured using the UCLA 3-item Loneliness Scale and social isolation was measured following a previous ELSA approach, and both sets of scores were categorised into low, medium, or high. Linear mixed methods and Cox proportional hazard modelling were used, adjusted for confounders.Findings The study sample consisted of 9171 participants at the baseline of Wave 2 (4083 male and 5088 female), with similar numbers in subsequent waves. In the fixed effect model, adjusted for marital status, age, gender, wealth, and smoking status, respondents with higher levels of loneliness had a higher frailty index score (beta coefficient 0006, 95% CI 0.006 to 0.007; p