Primary gastrointestinal non-Hodgkin's lymphoma in a population-based registry.
Primary gastrointestinal non-Hodgkin's lymphoma in a population-based registry.
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DOI：
10.1038/bjc.1989.351
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发表时间：
1989-11
影响因子：
8.8
通讯作者：
Willemze, R
中科院分区：
文献类型：
--
作者：
Otter, R;Bieger, R;Kluin, P M;Hermans, J;Willemze, R
在580例非霍奇金淋巴瘤（NHL）患者的基于人群的登记研究中，54例患者患有原发性胃淋巴瘤，42例肠道淋巴瘤，113例原发性结外淋巴瘤位于胃肠道以外的其他部位，371例原发性结内NHL。由病理学家小组审查组织学标本，并根据基尔分类法和国际工作分类法进行分类。原发性胃、肠、其他淋巴结和淋巴结NHL的4年生存率范围为50 - 60%; 4年无复发生存率分别为50%、35%、19%和19%。在局限性中度疾病患者中，胃NHL患者的生存率高于肠淋巴瘤患者。因为它是基于人群的，我们的研究队列没有因年龄、性能量表等而被排除，因此提供了人群中淋巴瘤发生和表现以及预后的更真实的情况。
In a population-based registry of 580 patients with non-Hodgkin's lymphoma (NHL) 54 patients had a primary gastric lymphoma, 42 an intestinal, 113 a primary extranodal lymphoma localised elsewhere than in the gastrointestinal tract and 371 a primary nodal NHL. Histological specimens were reviewed by a panel of pathologists and classified according to the Kiel classification and the International Working Formulation. The 4-year survival rates for primary gastric, intestinal, other extranodal and nodal NHL ranged from 50 to 60%; the 4-year recurrence-free survival rates were 50%, 35%, 19% and 19%, respectively. Among patients with localised intermediate-grade disease survival for those with gastric NHL was better than for those with intestinal lymphoma. Because it is population-based, our study cohort was not subjected to exclusion due to age, performance scale, etc. and therefore provides a more realistic picture of the occurrence and presentation of as well as prognosis for lymphoma in the population.