Pd-catalysed ortho-C-H Acylation/cross Coupling of 2-arylbenzo[d]thiazoles with Aldehydes Using tert-butyl Hydroperoxide as Oxidant
Pd-catalysed ortho-C-H Acylation/cross Coupling of 2-arylbenzo[d]thiazoles with Aldehydes Using tert-butyl Hydroperoxide as Oxidant
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DOI：
10.3184/174751913x13639769724276
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发表时间：
2013-05
影响因子：
1.4
通讯作者：
J. Wang;Ziyi Nie;Yan Li;Shuang Tan;Jia-Heng Jiang;P. Jiang;Q. Ding
中科院分区：
文献类型：
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作者：
J. Wang;Ziyi Nie;Yan Li;Shuang Tan;Jia-Heng Jiang;P. Jiang;Q. Ding
报道了一种钯催化的2-芳基苯并[d]噻唑与醛在叔丁基过氧化氢氧化下交叉偶联的C-H键直接酰化反应。该方法为直接由醛合成芳酮提供了一种有用的方法。此外，该反应可以耐受各种官能团，产率高，区域选择性高。
An efficient palladium-catalysed protocol for direct C–H bond acylation by cross coupling of 2-arylbenzo[d]thiazoles and aldehydes using tert-butyl hydroperoxide as the oxidant is reported. The process provides a useful method for the synthesis of aromatic ketones directly from aldehydes. In addition, the reaction can tolerate various functional groups in good yield with high regioselectivity.