Nanoparticle-functionalized porous polymer monolith detection elements for surface-enhanced Raman scattering.
Nanoparticle-functionalized porous polymer monolith detection elements for surface-enhanced Raman scattering.
复制标题
DOI：
10.1021/ac102932d
复制
发表时间：
2011-03-15
影响因子：
7.4
通讯作者：
DeVoe, Don L.
中科院分区：
文献类型：
--
作者：
Liu, Jikun;White, Ian;DeVoe, Don L.
本文介绍了用银纳米粒子功能化的多孔聚合物整体用于高灵敏度的表面增强拉曼散射(SERS)检测。SERS检测元件的制备是一个简单的过程，包括在二氧化硅毛细管中合成离散的聚合物整体段，然后在整体柱基质中物理捕获银纳米颗粒聚集体。结果表明，罗丹明6G(R6G)的SERS检测下限为220fmol，在24 h内具有良好的信号稳定性。通过对缓激肽和细胞色素c的测量，证明了SERS活性整体柱用于生物分子的无标记检测的能力。SERS活性整体柱可以很容易地集成到小型化的微型全分析系统中，用于各种生物传感、生物分析和生物医学应用的在线和无标记检测。
The use of porous polymer monoliths functionalized with silver nanoparticles is introduced in this work for high-sensitivity surface-enhanced Raman scattering (SERS) detection. Preparation of the SERS detection elements is a simple process comprising the synthesis of a discrete polymer monolith section within a silica capillary, followed by physically trapping silver nanoparticle aggregates within the monolith matrix. A SERS detection limit of 220 fmol for Rhodamine 6G (R6G) is demonstrated, with excellent signal stability over a 24 h period. The capability of the SERS-active monolith for label-free detection of biomolecules was demonstrated by measurements of bradykinin and cyctochrome c. The SERS-active monoliths can be readily integrated into miniaturized micro-total-analysis systems for on-line and label-free detection for a variety of biosensing, bioanalytical, and biomedical applications.
登录
查看更多内容
影响因子：
3
作者：
FOX, JW;VAVREK, RJ;STEWART, JM
通讯作者：
STEWART, JM
影响因子：
3.3
作者：
Keating, CD;Kovaleski, KM;Natan, MJ
通讯作者：
Natan, MJ
影响因子：
3.3
作者：
Lin, HH;Mock, J;Sailor, MJ
通讯作者：
Sailor, MJ
影响因子：
4.5
作者：
BEER, KD;TANNER, W;GARRELL, RL
通讯作者：
GARRELL, RL
影响因子：
4.1
作者：
Li, Yun;Gu, Binghe;Lee, Milton L.
通讯作者：
Lee, Milton L.