Calculation of glomerular filtration rate expressed in mL/min from plasma cystatin C values in mg/L
Calculation of glomerular filtration rate expressed in mL/min from plasma cystatin C values in mg/L
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DOI：
10.1080/00365510410003723
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发表时间：
2004-02-01
影响因子：
2.1
通讯作者：
Hansson, LO
中科院分区：
文献类型：
--
作者：
Larsson, A;Malm, J;Hansson, LO
Cockcroft-Gault公式通常用于根据血浆肌酐结果计算肾小球滤过率（GFR）。在瑞典，这种计算通常不在实验室进行，而是在当地病房进行。这些手动计算可能会导致错误的结果。在几项研究中，血浆胱抑素C已被证明在估计GFR方面优于血浆肌酐上级。使用胱抑素C作为GFR标志物的一个局限性是没有将以mg/L表示的胱抑素C转换为以mL/min表示的GFR的转换公式。在本研究中，将血浆肌酐和胱抑素C与碘海醇清除率进行比较。更强的相关性（p
The Cockcroft-Gault formula is often used to calculate the glomerular filtration rate (GFR) from plasma creatinine results. In Sweden this calculation is not usually done in the laboratory, but locally in the wards. These manual calculations could cause erroneous results. In several studies plasma cystatin C has been shown to be superior to plasma creatinine for estimation of GFR. One limitation of using cystatin C as a GFR marker is that there is no conversion formula transforming cystatin C expressed as mg/L to GFR expressed as mL/min. In this study plasma creatinine and cystatin C were compared with iohexol clearance. A stronger correlation (p