Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach.

Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach.
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心肌损伤的分子成像:磁荧光方法。

DOI:
10.1007/s12410-009-0005-x
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发表时间:
2009
影响因子:
0.9
通讯作者:
Sosnovik,DavidE
Sosnovik,DavidE
中科院分区:
--
文献类型:
--
作者:
Sosnovik,DavidE

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The role of molecular imaging in enhancing the understanding of myocardial injury and repair is rapidly expanding. Moreover, in recent years magnetic resonance and fluorescence-based approaches have been added to the molecular imaging armamentarium and have been used to image selected molecular and cellular targets in the myocardium. Apoptosis, necrosis, macrophage infiltration, myeloperoxidase activity, cathepsin activity, and type 1 collagen have all been imaged in vivo with a magnetofluorescent (MRI and/or fluorescence) approach. This review highlights the potential of these and other magnetofluorescent agents, with particular focus on their role in ischemic heart disease.
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