Management of necrotising enterocolitis

Management of necrotising enterocolitis
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坏死性小肠结肠炎的治疗

DOI:
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发表时间:
2003
影响因子:
5.2
通讯作者:
A. Fleischer
A. Fleischer
中科院分区:
医学2区
文献类型:
--
作者:
R. Balkrishnan;T. S. Housman;Christie L. Carroll;S. Feldman;A. Fleischer

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目的:使用经过验证的严重程度和家庭影响衡量指标,检查儿童特应性皮炎 (AD) 严重程度和家庭影响之间的关系(基线时和经专科医师干预后)。方法:对 49 名随机选择的 AD 儿童的父母/照顾者进行横断面自我调查; 35 名家长接受了随访。家庭影响是使用由父母/照顾者填写的修改后的 AD 家庭影响量表来衡量的。儿童疾病的严重程度是通过研究者通过湿疹面积和严重程度指数 (EASI) 进行的评估以及护理人员通过最近验证的自我评估湿疹面积和严重程度指数 (SA-EASI) 进行的评估来测量的。结果:父母-照顾者对儿童严重程度的评估是儿童 AD 对家庭影响的最显着相关性(基线时 p = 0.65,随访时 p = 0.38)。在多元回归模型中,父母-照顾者对严重程度的估计仍然是接受皮肤科医生护理前后家庭影响以及皮肤科医生护理前后影响差异的最强预测因素。结论:有证据支持 AD 儿童的父母/照顾者能够准确确定孩子 AD 的严重程度;感知的严重程度是这种情况对家庭影响的驱动因素。由专科医师对儿童进行治疗可以减少这种情况的严重程度以及对家庭的影响。
Aim: To examine the association between childhood atopic dermatitis (AD) severity and family impact at baseline and after an intervention by a physician specialist, using validated measures of both severity and family impact. Methods: Cross sectional self administered survey of parent–caregivers of 49 randomly selected children with AD; 35 parents were available for follow up. Family impact was measured using a modified AD Family Impact Scale completed by the parent–caregiver. The child’s disease severity was measured using both the investigator’s assessment via the Eczema Area and Severity Index (EASI) and the caregiver’s assessment via the recently validated Self Assessment Eczema Area and Severity Index (SA-EASI). Results: The parent–caregiver’s assessment of severity of the child was the most significant correlate of the family impact of the child’s AD (p = 0.65 at baseline and p = 0.38 at follow up). In multivariate regression models, the parent–caregiver’s estimate of severity remained the single strongest predictor of family impact before and after receipt of dermatologist care, as well as the difference in impact between pre and post-dermatologist care. Conclusions: There is evidence to support the ability of parent–caregivers of children with AD to accurately determine severity of their child’s AD; perceived severity is the driver of the family impact of this condition. Treatment of a child by a physician specialist is associated with reductions in both perceived severity, as well as family impact of this condition.