KAPOSI'S SARCOMA IN NIGERIA.
KAPOSI'S SARCOMA IN NIGERIA.
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DOI：
10.1038/bjc.1963.28
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发表时间：
1963-06
影响因子：
8.8
通讯作者：
MACLEAN, C M
中科院分区：
文献类型：
--
作者：
MACLEAN, C M
自卡波西于 1872 年在维也纳首次描述这种被他称为“特发性多色素肉瘤”的疾病以来的九十年间，有关卡波西肉瘤的文献数量不仅表明了这种疾病的模糊组织学状态和可疑的病因学，而且表明了其本质上的罕见性。 68年后，Choisser和Ramsey（1940）回顾欧美文献时，发现了600个案例的报道。 1922 年，在报道法属喀麦隆的第一例非洲病例时，Jojot 和 Laigret 印象深刻的不是这种特殊形式的恶性疾病的发现，而是该病例证明癌症确实发生在非洲，“这是他们观察到的诊断”，“总体而言，人们不会在该地区的黑人居民中考虑这一点”。自这一谨慎的声明发布以来，已收集了大量非洲卡波西肉瘤病例。 Quenum（1957）在评论该疾病的分布模式时指出，在赤道附近卡波西肉瘤的发病率有所增加，Davies（1959）进一步指出，“这种病在干燥的沙地地区相对罕见，但在潮湿的热带地区和高地高原上更为常见”。继续寻找环境影响。 Oettle (1962) 对非洲不同地区的卡波西肉瘤相对发病率进行了统计分析，他提到加纳、罗得西亚和法属西非的发病率较低（低于 1%），而南非联邦（0-8-2%）、尼日利亚（2-3%）、肯尼亚和乌干达（4-5%）的发病率较高，而刚果部分地区的发病率较高。 （4.3-10-4%）。
THE extent of the literature which has appeared on the subject of Kaposi's Sarcoma during the ninety years since Kaposi first described, from Vienna in 1872, the condition which he called" idiopathic multiple pigment sarcoma", has been indicative not only of the ambiguous histological status and dubious aetiology of this disease but also of its essential rarity. When, after 68 years, Choisser and Ramsey (1940) reviewed the European and American literature, they found reports of 600 cases. In reporting the first African case from the French Cameroons in 1922, Jojot and Laigret were impressed not so much by the dis-covery of this particular form of malignant disease as by the demonstration which the case afforded that cancer did occur at all in Africa," It is a diagnosis they observed," which, oIn the whole, one does not consider among the black inhabitants of this region". The large numbers of African cases of Kaposi's Sarcoma which have been collected since the time this cautious statement was made are summarised in Table I.Commenting upon the pattern of distribution of the disease which appeared to evolve from the African experience, Quenum (1957) suggested that the inci-dence of Kaposi's Sarcoma increased in proximity to the Equator. Davies (1959) went further when he remarked," It is comparatively rare in the dry sandy areas but commoner in the moister tropical areas and also on the upland plateaux". The search for an environmental influence was continued by Oettle (1962) who statistically analysed different African reports in terms of the relative frequency of Kaposi's Sarcoma amongst tumours from various territories. He referred to the low frequency in Ghana, Rhodesia and French West Africa (below 1 per cent), compared successively with the Union of South Africa (0-8-2 per cent), Nigeria (2-3 per cent), Kenya and Uganda (4-5 per cent) and with the high frequency in parts of the Congo (4.3-10-4 per cent).