Postpartum Depression: Current Status and Future Directions
Postpartum Depression: Current Status and Future Directions
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DOI：
10.1146/annurev-clinpsy-050212-185612
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发表时间：
2013-01-01
期刊：
影响因子：
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通讯作者：
McCabe, Jennifer E.
中科院分区：
文献类型：
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作者：
O'Hara, Michael W.;McCabe, Jennifer E.
产后抑郁症（PPD）是一种常见且严重的心理健康问题，与母亲的痛苦和对后代的许多负面影响有关。分娩后的前六个月可能是抑郁症的高危时期。患病率估计为13%至19%。风险因素反映了那些典型的重度抑郁症，除了产后特异性因素，如对激素变化的敏感性。心理干预的对照试验已经验证了各种个人和团体干预。药物治疗通常会导致抑郁症的改善，但在对照试验中，药物治疗条件下的患者与安慰剂或活性对照条件下的患者之间的结果通常没有显著差异。综述集中在对母乳喂养时使用的特定抗抑郁药物的建议上。预防产后抑郁症是可行和有效的。最后，越来越多的人将心理健康检查纳入孕妇和产后妇女的日常初级保健，并在检查后进行治疗或转诊和后续护理。研究和临床建议在整个审查。
Postpartum depression (PPD) is a common and serious mental health problem that is associated with maternal suffering and numerous negative consequences for offspring. The first six months after delivery may represent a high-risk time for depression. Estimates of prevalence range from 13% to 19%. Risk factors mirror those typically found with major depression, with the exception of postpartum-specific factors such as sensitivity to hormone changes. Controlled trials of psychological interventions have validated a variety of individual and group interventions. Medication often leads to depression improvement, but in controlled trials there are often no significant differences in outcomes between patients in the medication condition and those in placebo or active control conditions. Reviews converge on recommendations for particular antidepressant medications for use while breastfeeding. Prevention of PPD appears to be feasible and effective. Finally, there is a growing movement to integrate mental health screening into routine primary care for pregnant and postpartum women and to follow up this screening with treatment or referral and with follow-up care. Research and clinical recommendations are made throughout this review.