INTEGRATED HUMAN GENOME-WIDE MAPS CONSTRUCTED USING THE CEPH REFERENCE PANEL
INTEGRATED HUMAN GENOME-WIDE MAPS CONSTRUCTED USING THE CEPH REFERENCE PANEL
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DOI：
10.1038/ng0494-391
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发表时间：
1994-04-01
期刊：
影响因子：
30.8
通讯作者：
MURRAY, JC
中科院分区：
文献类型：
--
作者：
BUETOW, KH;WEBER, JL;MURRAY, JC
High resolution linkage maps have proven to be invaluable tools in genetic investigations. We have assembled a collection of genetic maps constructed from primary data collected from investigators performing genotyping using the Centre Etude Polymorphism Humain (CEPH) reference pedigree panel. These maps were constructed using a rigorous, semi-automated map construction algorithm that evaluates the integrity of the maps during construction. Two classes of maps were produced: a high confidence ''skeletal'' set composed of 544 PCR based markers, and a more highly annotated ''framework'' set containing maps of 1,123 markers. Genetic map locations within the framework maps are provided for an additional 1,758 loci without statistically unique interval assignments.
