The burden of antenatal heart disease in South Africa: a systematic review.
The burden of antenatal heart disease in South Africa: a systematic review.
复制标题
DOI：
10.1186/1471-2261-12-23
复制
发表时间：
2012-03-30
影响因子：
2.1
通讯作者：
Mayosi BM
中科院分区：
文献类型：
--
作者：
Watkins DA;Sebitloane M;Engel ME;Mayosi BM
南非的孕产妇死亡率正在上升，心脏病目前占间接死亡原因的41%。对南非孕妇的心脏病负担知之甚少。我们系统地回顾了当代流行病学和围产期结果的心脏病在南非妇女参加产前保健。检索在PubMed、ISI Web of Science、EBSCO Africa-Wide数据库、南非联合目录和当前和已完成研究数据库（南非）中进行。还手动检索了纳入文献的参考文献。报告南非产前心脏病流行病学数据的研究也包括在内。还收集了关于发病率和死亡率的数据。7项研究被纳入系统综述。心脏病的患病率从每10万名分娩123人到943人不等，中位患病率为每10万人616人。风湿性瓣膜病变是最常见的异常，尽管与其他发展中国家相比，心肌病的发病率高得不成比例。在获得护理机会有限的地区，围产期病死率高达9.5%。最常见的并发症是肺水肿、血栓栓塞和华法林使用引起的大出血。围产期死亡率为8.9%至23.8%，而二尖瓣病变与低出生体重有关。由于纳入研究的临床和统计异质性，无法进行荟萃分析。大约0.6%的南非孕妇有预先存在的心脏异常，风湿性病变是最常见的。产妇和围产期发病率和死亡率仍然很高。我们总结了目前文献的局限性，并建议标准的报告标准，为未来的报告，这一审查。
Maternal mortality in South Africa is rising, and heart conditions currently account for 41 per cent of indirect causes of deaths. Little is known about the burden of heart disease in pregnant South Africans. We systematically reviewed the contemporary epidemiology and peripartum outcomes of heart disease in South African women attending antenatal care. Searches were performed in PubMed, ISI Web of Science, the EBSCO Africa-Wide database, the South African Union Catalogue, and the Current and Completed Research database (South Africa). References of included articles were also hand-searched. Studies reporting epidemiologic data on antenatal heart disease in South Africa were included. Data on morbidity and mortality were also collected. Seven studies were included in the systematic review. The prevalence of heart disease ranged from 123 to 943 per 100,000 deliveries, with a median prevalence of 616 per 100,000. Rheumatic valvular lesions were the commonest abnormalities, although cardiomyopathies were disproportionately high in comparison with other developing countries. Peripartum case-fatality rates were as high as 9.5 per cent in areas with limited access to care. The most frequent complications were pulmonary oedema, thromboembolism, and major bleeding with warfarin use. Perinatal mortality ranged from 8.9 to 23.8 per cent, whilst mitral lesions were associated with low birth weight. Meta-analysis could not be performed due to clinical and statistical heterogeneity of the included studies. Approximately 0.6 per cent of pregnant South Africans have pre-existing cardiac abnormalities, with rheumatic lesions being the commonest. Maternal and perinatal morbidity and mortality continue to be very high. We conclude this review by summarising limitations of the current literature and recommending standard reporting criteria for future reports.
登录
查看更多内容
影响因子：
3
作者：
Diao, Maboury;Kane, Adama;Ba, Serigne Abdou
通讯作者：
Ba, Serigne Abdou
影响因子：
24
作者：
Tanous, David;Siu, Samuel C.;Silversides, Candice K.
通讯作者：
Silversides, Candice K.
DOI：
10.1016/j.ijgo.2005.03.008
发表时间：
2005-07-01
影响因子：
3.8
作者：
Abdel-Hady, ES;El-Shamy, M;Moussa, S
通讯作者：
Moussa, S
DOI：
10.1111/j.1471-0528.2000.tb10395.x
发表时间：
2000-08-01
期刊：
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
影响因子：
--
作者：
Desai, DK;Adanlawo, M;Kleinschmidt, I
通讯作者：
Kleinschmidt, I
DOI：
10.1016/s0020-7292(99)00006-5
发表时间：
1999-03-01
影响因子：
3.8
作者：
Divanovic, E;Buchmann, EJ
通讯作者：
Buchmann, EJ