Mycoplasma pneumoniae pneumonia in hospitalized children diagnosed at acute stage by paired sera
Mycoplasma pneumoniae pneumonia in hospitalized children diagnosed at acute stage by paired sera
复制标题
DOI：
10.3760/cma.j.issn.0366-6999.2010.23.013
复制
发表时间：
2010-12-05
影响因子：
6.1
通讯作者：
Liu Zhen-ye
中科院分区：
文献类型：
--
作者：
Liu Chun-ling;Wang Gui-qiang;Liu Zhen-ye
肺炎支原体（M pneumoniae）是呼吸道感染的常见原因。对肺炎支原体感染的临床表现了解不足，我们对抗体滴度均升高>= 4倍的住院儿童肺炎支原体肺炎的临床和实验室结果进行了描述。方法对住院1年的急性呼吸道感染患儿常规检测肺炎支原体抗体，并对抗体滴度升高>= 4倍的患儿重新收集病史床边的一个人,他们的冷冻配对血清样本的肺炎支原体抗体titerResults再次测量的635名儿童的血清检测肺炎支原体抗体配对血清得到从82年29 3%(24/82)有> = 4倍提高抗体效价有24例9个男生和15个女生,年龄从2到14年,其血清样本在第二天9最早症状出现后,最短间隔三天所有儿童出现高烧(> = 5 38摄氏度)和咳嗽20一个没有鼻塞或流鼻涕和五个有轻微的头痛,所有相关的疾病比较严重的高烧39如果峰值温度> 5摄氏度所有被诊断为肺炎通过胸部x光检查四举行了双边或multilobar参与和峰值温度都是39 5摄氏度)是相关的儿童肺炎支原体肺炎的严重程度
Background Mycoplasma pneumoniae (M pneumoniae) is a frequent cause of respiratory tract infections However, there is deficient knowledge about the clinical manifestations of M pneumoniae infection We described the clinical and laboratory findings of M pneumoniae pneumonia in hospitalized children who were all diagnosed by a >= fourfold increase in antibody titerMethods M pneumoniae antibodies were routinely detected in children admitted with acute respiratory infection during a one-year period The medical history was re-collected from children whose M pneumoniae antibody titer increased >= fourfold at the bedside by a single person, and their frozen paired serum samples were measured again for the M pneumoniae antibody titerResults Of the 635 children whose sera were detected for the M pneumoniae antibody paired sera were obtained from 82 and 29 3% (24/82) showed a >= fourfold increase in antibody titer There were 24 cases nine boys and 15 girls, aged from two to 14 years, whose second serum samples were taken on day 9 at the earliest after symptom onset, the shortest interval was three days All children presented with a high fever (>= 38 5 degrees C) and coughing Twenty one had no nasal obstruction or a runny nose and five had mild headaches which all were associated with the high fever The disease was comparatively severe if the peak temperature was >39 5 degrees C All were diagnosed as having pneumonia through chest X-rays Four had bilateral or multilobar involvement and their peak temperatures were all 39 5 degrees C) is correlated with the severity of M pneumoniae pneumonia in children