Evaluating self-generated information: Anterior prefrontal contributions to human cognition
Evaluating self-generated information: Anterior prefrontal contributions to human cognition
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DOI：
10.1037/0735-7044.117.6.1161
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发表时间：
2003-12-01
影响因子：
1.9
通讯作者：
Gabrieli, JDE
中科院分区：
文献类型：
--
作者：
Christoff, K;Ream, JM;Gabrieli, JDE
在复杂的认知任务中，包括推理、长期记忆提取和工作记忆，前额叶前部或前额叶外侧皮层（RLPFC）经常被调动。作者报告了一项与事件相关的功能性MRI研究，表明RLPFC特别参与内部生成信息的评估，或者那些不能从外部环境中轻易感知但必须推断或自我生成的信息。研究结果与侧前额叶组织的层次模型一致，RLPFC只在最高阶的认知转换中起作用。RLPFC功能的这种特征可能有助于解释在多个认知领域中看似不同的发现，并可能为该区域对人类认知的贡献提供统一的解释。
The anterior or rostrolateral prefrontal cortex (RLPFC) is frequently recruited during complex cognitive tasks across a wide range of domains, including reasoning, long-term memory retrieval, and working memory. The authors report an event-related functional MRI study, indicating that the RLPFC is specifically involved in the evaluation of internally generated information-or information that cannot be readily perceived from the external environment but has to be inferred or self-generated. The findings are consistent with a hierarchical model of lateral prefrontal organization, with RLPFC contributing only at the highest orders of cognitive transformations. This characterization of RLPFC function may help explain seemingly disparate findings across multiple cognitive domains and could provide a unified account of this region's contribution to human cognition.