Quantitative changes in dietary fat intake and serum cholesterol in women: results from a randomized, controlled trial.
Quantitative changes in dietary fat intake and serum cholesterol in women: results from a randomized, controlled trial.
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女性膳食脂肪摄入量和血清胆固醇的定量变化：随机对照试验的结果。
DOI：
10.1093/ajcn/52.3.470
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
D. Tritchler
中科院分区：
文献类型：
--
作者：
N. F. Boyd;Mary Cousins;M. Beatón;V. Kriukov;G. Lockwood;D. Tritchler
我们比较了在低脂肪、高碳水化合物饮食的随机对照试验中，患有乳房X光摄影不良的女性在12个月内观察到的和预测的血清胆固醇变化，其中总脂肪摄入量从平均占卡路里的37%减少到21%，碳水化合物摄入量从占卡路里的44%增加到52%。观察到的血清胆固醇变化大于(根据Hegsted和Keys公式预测的)人群中初始血胆固醇值在上三分位数的受试者，与基线值在中三分位数的受试者预测的变化没有显著差异，而显著小于初值在下三分位数的受试者的预测。这些结果表明，血清胆固醇作为女性膳食脂肪摄入量变化的标志是否有用，取决于研究人群中血清胆固醇值的分布。
We compared observed and predicted changes in serum cholesterol in women with mammographic dysplasia who participated for 12 mo in a randomized, controlled trial of a low-fat, high-carbohydrate diet, in which total fat intake was reduced from an average of 37% of calories to 21% and carbohydrate intake increased from 44% to 52% of calories. Changes observed in serum cholesterol were greater than those predicted (by the formulas of Hegsted and Keys) for subjects with initial serum cholesterol values in the upper tertile of the population, were not significantly different from those predicted for subjects with baseline values in the middle tertile, and were significantly less than those predicted for subjects with initial values in the lower tertile. These results show that the usefulness of serum cholesterol as a marker of change in dietary fat intake in women depends on the distribution of serum cholesterol values in the population studied.
膳食脂肪水平对小鼠乳腺发育和激素反应性的影响。
影响因子：
11.2
作者：
Welsch,CW;DeHoog,JV;O'Connor,DH;Sheffield,LG
通讯作者：
Sheffield,LG