A complete implementation of list-mode reconstruction for PET
A complete implementation of list-mode reconstruction for PET
复制标题
PET 列表模式重建的完整实现
DOI：
10.13538/j.1001-8042/nst.23.219-225
复制
发表时间：
2012
影响因子：
2.8
通讯作者：
Zhao Shujun
中科院分区：
文献类型：
--
作者：
Zhang Bin;Shan Baoci;Yun Mingkai;Zhao Shujun
断层扫描重建算法是正电子发射断层扫描（PET）扫描仪的关键组成部分之一，大多数PET扫描仪都使用当前的sinograms数据中的数据中使用统计迭代重建算法。但是层析成像重建usin
Tomography reconstruction algorithm is one of the key components of positron emission tomography (PET) scanners, most PET scanners use statistical iterative reconstruction algorithms from data in sinograms currently. However tomography reconstruction using list-mode data has many unique advantages, in recent years great attention has been paid to it, being in the process of rapid development and improvement. In this paper, using experimental data of small animal PET scanner Eplus-166, exploiting ordinary subsetized list-mode EM (S-LMEM) algorithm and orthogonal distance-based ray-tracer (OD-RT), we eventually achieve list-mode tomography reconstruction. System response matrix (SRM), which establishes mapping relationship between the image and the projection space, is one key problem in iterative reconstruction algorithm. OD-RT is based on an optimization Siddon's algorithm to calculate the SRM, generating line-of-response (LOR) which is approximately Gaussian-shaped, achieving better modeling of detector response function (DRF). The results demonstrate that image resolution recovery achieves the inherent properties of the scanner and that on-the-fly ray-tracer for real-time calculation of system response matrix is feasible for dynamic reconstruction. Meanwhile, the optimal parameters for calculating SRM are found by experiments.