Idiopathic thrombocytopenic purpura and MMR vaccine
Idiopathic thrombocytopenic purpura and MMR vaccine
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DOI：
10.1136/adc.84.3.227
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发表时间：
2001-03-01
影响因子：
5.2
通讯作者：
Taylor, B
中科院分区：
文献类型：
--
作者：
Miller, E;Waight, P;Taylor, B
麻疹-腮腺炎-风疹（MMR）疫苗与特发性血小板减少性紫癜（ITP）之间的因果关系通过免疫接种/住院记录联系得到证实。接种疫苗后6周内的绝对风险为1 / 22 300剂，每3例中有2例发生在接种疫苗后6周，是由MMR疫苗引起的。在MMR之前患有ITP的儿童没有疫苗相关的复发。
A causal association between measles-mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.