The effects of partial sleep deprivation on energy balance: a systematic review and meta-analysis
The effects of partial sleep deprivation on energy balance: a systematic review and meta-analysis
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DOI：
10.1038/ejcn.2016.201
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发表时间：
2017-05-01
影响因子：
4.7
通讯作者：
Pot, G. K.
中科院分区：
文献类型：
--
作者：
Al Khatib, H. K.;Harding, S. V.;Pot, G. K.
背景/目的：尚不清楚短睡眠时间是否会导致体重增加。研究部分睡眠剥夺（PSD）对能量平衡成分的影响报告了相互矛盾的结果。我们的目的是对人类干预研究进行系统回顾和荟萃分析，评估PSD对能量摄入（EI）和能量消耗（EE）的影响。主题/方法：检索EMBASE、Medline、Cochrane CENTRAL、Web of Science和Scopus。与对照条件相比，PSD后EI和总EE的差异使用随机效应模型的逆方差法产生。次要结果包括常量营养素分布和静息代谢率。异质性用i -2统计量量化。结果：17项研究（n = 496）符合纳入系统评价的条件，11项研究（n = 172）提供了足够的数据纳入meta分析。与对照组相比，PSD组EI显著增加385 kcal（95%可信区间：252,517;P < 0.00001）。我们发现PSD对总EE和静息代谢率没有显著的影响。观察到的EI增加伴随着显著的高脂肪和低蛋白质摄入量，但对碳水化合物摄入量没有影响。结论：具有可提取数据的研究的综合效应表明，PSD导致EI增加，而对EE没有影响，导致净正能量平衡，从长远来看可能有助于体重增加。
BACKGROUND/OBJECTIVES: It is unknown whether short sleep duration causatively contributes to weight gain. Studies investigating effects of partial sleep deprivation (PSD) on energy balance components report conflicting findings. Our objective was to conduct a systematic review and meta-analysis of human intervention studies assessing the effects of PSD on energy intake (EI) and energy expenditure (EE).SUBJECTS/METHODS: EMBASE, Medline, Cochrane CENTRAL, Web of Science and Scopus were searched. Differences in EI and total EE following PSD compared with a control condition were generated using the inverse variance method with random-effects models. Secondary outcomes included macronutrient distribution and resting metabolic rate. Heterogeneity was quantified with the I-2-statistic.RESULTS: Seventeen studies (n = 496) were eligible for inclusion in the systematic review, and 11 studies (n = 172) provided sufficient data to be included in meta-analyses. EI was significantly increased by 385 kcal (95% confidence interval: 252, 517; P < 0.00001) following PSD compared with the control condition. We found no significant change in total EE or resting metabolic rate as a result of PSD. The observed increase in EI was accompanied by significantly higher fat and lower protein intakes, but no effect on carbohydrate intake.CONCLUSIONS: The pooled effects of the studies with extractable data indicated that PSD resulted in increased EI with no effect on EE, leading to a net positive energy balance, which in the long term may contribute to weight gain.