Capillaroscopy and videocapillaroscopy assessment of skin microcirculation: dermatologic and cosmetic approaches.
Capillaroscopy and videocapillaroscopy assessment of skin microcirculation: dermatologic and cosmetic approaches.
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DOI：
10.1111/j.1473-2165.2005.00303.x
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发表时间：
2005-09-01
影响因子：
2.3
通讯作者：
Aubin, Francois
中科院分区：
文献类型：
--
作者：
Humbert, Philippe;Sainthillier, Jean-Marie;Aubin, Francois
背景：不同的非侵入性生物工程技术存在研究皮肤的微血管和微循环的动力学。这些技术的目标是使皮肤毛细血管循环容易且直接地可视化。事实上，这些信息对于研究皮肤毛细血管循环的生理学和病理生理学是不可替代的。AIMS：毛细血管镜和视频毛细血管镜技术以不同的方法研究皮肤的毛细血管结构。在这项工作中提出的方法包括图像处理分析结合形态学，统计学，几何，和神经网络检测，旨在量化微循环并跟踪其演变。为了说明这些技术和方法的组合，它们的应用程序的不同的例子进行了描述，在皮肤病学（高血压，静脉功能不全，年龄相关的变化），以及在美容（酒渣鼻和红斑评估）。结论：皮肤微循环的结构或动态变化的测定属于非侵入性技术的生物计量领域。因此，可以观察到由局部化妆品或化学试剂引起的每一种毛细血管修饰。在病理学中，使用该系统可以更好地检查许多情况。与数字图像分析的潜力，毛细血管镜技术可能会扩大其应用领域的评估的影响，动脉和静脉疾病的皮肤营养循环。
BACKGROUND: Different noninvasive bioengineering techniques exist to study the microvasculature of the skin and the dynamics of the microcirculation. The goal of these techniques is to visualize the skin capillary circulation easily and directly. Indeed, this information is irreplaceable to study the physiology and physiopathology of the skin capillary circulation efficiently.AIMS: Capillaroscopy and video-capillaroscopy techniques are presented with different methods to study the capillary structure of the skin.METHODS: The methods presented in this work include image processing analysis combining morphology, statistics, geometry, and neural network detection designed to quantify the microcirculation and to follow its evolution. To illustrate the combination of these techniques and methods, different examples of their application are described, in dermatology (hypertension, venous insufficiency, age-related changes) as well as in cosmetology (rosacea and erythrosis assessment).CONCLUSION: The determination of structural or dynamic changes in the cutaneous microcirculation belongs to the noninvasive techniques of the biometrological domain. Thus, every capillary modification resulting from topical cosmetic products, or chemical agents can be observed. In pathology, numerous conditions can be better examined with this system. Associated with the potential of numerical image analysis, capillaroscopy techniques will probably extend their application fields to the assessment of the influence of arterial and venous diseases on the skin nutritional circulation.